Identifying Transcripts with Tandem Duplications from RNA-Sequencing Data to Predict BRCA1-Type Primary Breast Cancer

SIMPLE SUMMARY: Homologous recombination repair deficiency (HRD) is a biomarker for the response to PARP inhibitor anti-cancer treatment. Therefore, methods that detect the HRD phenotype in cancers in a (cost-)effective manner are pivotal. In this respect, the HRDetect and CHORD algorithms were deve...

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Detalles Bibliográficos
Autores principales: Qu, Shuoying, Martens, John W. M., Hollestelle, Antoinette, Smid, Marcel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8833645/
https://www.ncbi.nlm.nih.gov/pubmed/35159019
http://dx.doi.org/10.3390/cancers14030753

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8833645/
https://www.ncbi.nlm.nih.gov/pubmed/35159019
http://dx.doi.org/10.3390/cancers14030753

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