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Strategies for Improving the Efficacy of CAR T Cells in Solid Cancers

SIMPLE SUMMARY: Cell therapy with genetically retargeted T cells shows strong clinical efficacy against leukaemia and lymphoma. To make this therapy efficient against solid cancers, a series of hurdles must be addressed. This includes the need to enable the T cells to survive long term in patients a...

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Detalles Bibliográficos
Autor principal: Kyte, Jon Amund
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8833730/
https://www.ncbi.nlm.nih.gov/pubmed/35158839
http://dx.doi.org/10.3390/cancers14030571