Synthesis of Biotinylated PAMAM G3 Dendrimers Substituted with R-Glycidol and Celecoxib/Simvastatin as Repurposed Drugs and Evaluation of Their Increased Additive Cytotoxicity for Cancer Cell Lines

SIMPLE SUMMARY: New anti-cancer drugs can be created through the combination of well-known substances acting on different molecular targets. Repurposed drugs selected in this way can then be attached to special carriers that have specific, high affinity for cancer cells. In this study, two anti-glio...

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Detalles Bibliográficos
Autores principales: Wróbel, Konrad, Wołowiec, Stanisław, Markowicz, Joanna, Wałajtys-Rode, Elżbieta, Uram, Łukasz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8833738/
https://www.ncbi.nlm.nih.gov/pubmed/35158983
http://dx.doi.org/10.3390/cancers14030714

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8833738/
https://www.ncbi.nlm.nih.gov/pubmed/35158983
http://dx.doi.org/10.3390/cancers14030714

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