Primaquine as a Candidate for HHV-8-Associated Primary Effusion Lymphoma and Kaposi’s Sarcoma Treatment

SIMPLE SUMMARY: Primaquine diphosphate is introduced as a promising therapeutic candidate for HHV-8-associated diseases by inducing specific cytotoxicity in vitro through ROS- and ER stress-mediated apoptosis. PQ presented a promising anti-tumor effect in an in vivo PEL mouse model and in KS patient...

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Detalles Bibliográficos
Autores principales: Gothland, Adélie, Leducq, Valentin, Grange, Philippe, Faye, Ousmane, Beauvais Remigereau, Laurianne, Sayon, Sophie, Désiré, Nathalie, Jary, Aude, Laplantine, Emmanuel, Maiga, Almoustapha Issiaka, Dupin, Nicolas, Marcelin, Anne-Geneviève, Calvez, Vincent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8833810/
https://www.ncbi.nlm.nih.gov/pubmed/35158811
http://dx.doi.org/10.3390/cancers14030543

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