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NSAIDs Overcome PIK3CA Mutation-Mediated Resistance to EGFR Inhibition in Head and Neck Cancer Preclinical Models
SIMPLE SUMMARY: Epidermal growth factor receptor (EGFR) inhibitors are approved by the Food and Drug Administration (FDA) for the treatment of several cancers including head and neck squamous cell carcinoma (HNSCC). It has been reported that activating mutations in PIK3CA, which are relatively commo...
Autores principales: | Li, Hua, Peyser, Noah D., Zeng, Yan, Ha, Patrick K., Johnson, Daniel E., Grandis, Jennifer R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8833811/ https://www.ncbi.nlm.nih.gov/pubmed/35158773 http://dx.doi.org/10.3390/cancers14030506 |
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