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Nuclear Localization Sequence of FGF1 Is Not Required for Its Intracellular Anti-Apoptotic Activity in Differentiated Cells

Fibroblast growth factor 1 (FGF1) is considered primarily as a ligand for FGF surface receptors (FGFRs) through which it activates a number of cellular responses. In addition to its canonical mode of action, FGF1 can act intracellularly, before secretion or after internalization and translocation fr...

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Detalles Bibliográficos
Autores principales: Lampart, Agata, Sluzalska, Katarzyna Dominika, Czyrek, Aleksandra, Szerszen, Aleksandra, Otlewski, Jacek, Wiedlocha, Antoni, Zakrzewska, Malgorzata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8833943/
https://www.ncbi.nlm.nih.gov/pubmed/35159330
http://dx.doi.org/10.3390/cells11030522