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Prkci Regulates Autophagy and Pancreatic Tumorigenesis in Mice

SIMPLE SUMMARY: Pancreatic cancer is a highly fatal disease that does not respond well to current cancer therapies. We previously showed that protein kinase C iota (PKCι) is highly expressed in pancreatic cancer, and inhibition of PKCι signaling in human pancreatic cell lines blocks tumor growth. In...

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Detalles Bibliográficos
Autores principales: Inman, Kristin S., Liu, Yi, Scotti Buzhardt, Michele L., Leitges, Michael, Krishna, Murli, Crawford, Howard C., Fields, Alan P., Murray, Nicole R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8834021/
https://www.ncbi.nlm.nih.gov/pubmed/35159064
http://dx.doi.org/10.3390/cancers14030796