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Down-Regulation of the Longevity-Associated Protein SIRT1 in Peripheral Blood Mononuclear Cells of Treated HIV Patients

The activity of sirtuin 1 (SIRT1), a class III histone deacetylase with a critical role in several biological functions, decreases with age and its deficiency is associated with many inflammatory and age-related diseases. It also regulates the chronic immune activation and viral latency during an HI...

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Detalles Bibliográficos
Autores principales: Gruevska, Aleksandra, Moragrega, Ángela B., Galindo, María J., Esplugues, Juan V., Blas-García, Ana, Apostolova, Nadezda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8834054/
https://www.ncbi.nlm.nih.gov/pubmed/35159154
http://dx.doi.org/10.3390/cells11030348