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Down-Regulation of the Longevity-Associated Protein SIRT1 in Peripheral Blood Mononuclear Cells of Treated HIV Patients
The activity of sirtuin 1 (SIRT1), a class III histone deacetylase with a critical role in several biological functions, decreases with age and its deficiency is associated with many inflammatory and age-related diseases. It also regulates the chronic immune activation and viral latency during an HI...
Autores principales: | Gruevska, Aleksandra, Moragrega, Ángela B., Galindo, María J., Esplugues, Juan V., Blas-García, Ana, Apostolova, Nadezda |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8834054/ https://www.ncbi.nlm.nih.gov/pubmed/35159154 http://dx.doi.org/10.3390/cells11030348 |
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