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TRIM32 Deficiency Impairs the Generation of Pyramidal Neurons in Developing Cerebral Cortex
Excitatory-inhibitory imbalance (E/I) is a fundamental mechanism underlying autism spectrum disorders (ASD). TRIM32 is a risk gene genetically associated with ASD. The absence of TRIM32 causes impaired generation of inhibitory GABAergic interneurons, neural network hyperexcitability, and autism-like...
Autores principales: | Sun, Yan-Yun, Chen, Wen-Jin, Huang, Ze-Ping, Yang, Gang, Wu, Ming-Lei, Xu, De-En, Yang, Wu-Lin, Luo, Yong-Chun, Xiao, Zhi-Cheng, Xu, Ru-Xiang, Ma, Quan-Hong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8834167/ https://www.ncbi.nlm.nih.gov/pubmed/35159260 http://dx.doi.org/10.3390/cells11030449 |
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