Cargando…

Glioma Stem Cells Upregulate CD39 Expression to Escape Immune Response through SOX2 Modulation

SIMPLE SUMMARY: Glioblastoma is the most malignant tumor of the central nervous system. Glioma stem cells are the cause of adverse outcomes such as early recurrence and low overall survival in glioma patients. Targeting glioma stem cells is considered a promising anti-glioma strategy, Although CD39...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Bin, Cao, Yufei, Li, Yanyan, Ma, Haifeng, Yang, Mingfei, Zhang, Qiang, Li, Guofeng, Zhang, Kai, Wu, Yue, Zhou, Youxin, Yang, Wei, Sun, Ting
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8834269/ https://www.ncbi.nlm.nih.gov/pubmed/35159053 http://dx.doi.org/10.3390/cancers14030783

Ejemplares similares

Role of HC-gp39 in chondrogenesis: upregulation of SOX-9 expression by HC-gp39 in mouse chondrocytes
por: Jacques, C, et al.
Publicado: (2003)

Enhanced radiation-induced immunogenic cell death activates chimeric antigen receptor T cells by targeting CD39 against glioblastoma
por: Sun, Ting, et al.
Publicado: (2022)

Aggressive invasion is observed in CD133(−)/A2B5(+) glioma-initiating cells
por: SUN, TING, et al.
Publicado: (2015)

G9a promotes immune suppression by targeting the Fbxw7/Notch pathway in glioma stem cells
por: Cao, Yufei, et al.
Publicado: (2023)

Interleukin-6 upregulates SOX18 expression in osteosarcoma
por: Wu, Zhong, et al.
Publicado: (2017)

Targeting glioma stem cells enhances anti-tumor effect of boron neutron capture therapy
por: Sun, Ting, et al.
Publicado: (2016)

The TGF‐b/SOX4 axis and ROS‐driven autophagy co‐mediate CD39 expression in regulatory T‐cells
por: Gerner, Marlene C., et al.
Publicado: (2020)

Long Non-Coding RNA SNHG6 Supports Glioma Progression Through Upregulation of Notch1, Sox2, and EMT
por: Nie, Jing, et al.
Publicado: (2021)

Knockdown of long non-coding RNA NEAT1 inhibits glioma cell migration and invasion via modulation of SOX2 targeted by miR-132
por: Zhou, Ke, et al.
Publicado: (2018)

miR-218-5p inhibits the stem cell properties and invasive ability of the A2B5+CD133- subgroup of human glioma stem cells
por: Wu, Zhiwu, et al.
Publicado: (2022)

SOX2 downregulation of PML increases HCMV gene expression and growth of glioma cells
por: Wen, Le, et al.
Publicado: (2023)

Review immune response of targeting CD39 in cancer
por: Liu, Yao, et al.
Publicado: (2023)

CD39 is upregulated during activation of mouse and human T cells and attenuates the immune response to Listeria monocytogenes
por: Raczkowski, Friederike, et al.
Publicado: (2018)

Histone deacetylase inhibition up-regulates MHC class I to facilitate cytotoxic T lymphocyte-mediated tumor cell killing in glioma cells
por: Sun, Ting, et al.
Publicado: (2019)

Rac1 promotes the reprogramming of glucose metabolism and the growth of colon cancer cells through upregulating SOX9
por: Liang, Jiaxin, et al.
Publicado: (2022)

Knockdown of SLC39A14 inhibits glioma progression by promoting erastin-induced ferroptosis SLC39A14 knockdown inhibits glioma progression
por: Zhang, Yunwen, et al.
Publicado: (2023)

Radiation-induced upregulation of telomerase activity escapes PI3-kinase inhibition in two malignant glioma cell lines
por: MILLET, P., et al.
Publicado: (2013)

Experimental study of selective MGMT peptides mimicking TMZ drug resistance in glioma
por: Wu, Yue, et al.
Publicado: (2022)

SOX2 Promotes Brain Metastasis of Breast Cancer by Upregulating the Expression of FSCN1 and HBEGF
por: Xiao, Weikai, et al.
Publicado: (2020)

Upregulation of SATB1 is associated with the development and progression of glioma
por: Chu, Sheng-Hua, et al.
Publicado: (2012)

Upregulation of SOX4 antagonizes cellular senescence in esophageal squamous cell carcinoma
por: Han, Rongfei, et al.
Publicado: (2016)

Advances in research on immune escape mechanism of glioma
por: Guo, Xu, et al.
Publicado: (2023)

Genetic variants of SOX9 contribute to susceptibility of gliomas among Chinese population
por: Wang, Liang, et al.
Publicado: (2016)

The role of lysosomal peptidases in glioma immune escape: underlying mechanisms and therapeutic strategies
por: Liu, Hao, et al.
Publicado: (2023)

Glioma SOX2 expression decreased after adjuvant therapy
por: Yu, Wei, et al.
Publicado: (2019)

CD39 in the development and progression of pulmonary arterial hypertension
por: Willcox, Abbey, et al.
Publicado: (2022)

CD8+CD39+ T Cells Mediate Anti-Tumor Cytotoxicity in Bladder Cancer
por: Zhu, Wenjie, et al.
Publicado: (2021)

KRAS mutation-induced upregulation of PD-L1 mediates immune escape in human lung adenocarcinoma
por: Chen, Nan, et al.
Publicado: (2017)

CD39 Regulation and Functions in T Cells
por: Timperi, Eleonora, et al.
Publicado: (2021)

Telmisartan Mitigates TNF-α-Induced Type II Collagen Reduction by Upregulating SOX-9
por: Zhang, Xiuying, et al.
Publicado: (2021)

Prognostic Value of CD133 and SOX2 in Advanced Cancer
por: Han, Susu, et al.
Publicado: (2019)

YAP promotes autophagy and progression of gliomas via upregulating HMGB1
por: Zhao, Min, et al.
Publicado: (2021)

Electroacupuncture Upregulates HIF-1α and SOX9 Expression in Knee Osteoarthritis
por: Tong, Jie, et al.
Publicado: (2021)

The Upregulation of Molecules Related to Tumor Immune Escape in Human Pituitary Adenomas
por: Xi, Zhiyu, et al.
Publicado: (2021)

What Else Can CD39 Tell Us?
por: Zhao, Hai, et al.
Publicado: (2017)

CD39: the potential target in small cell lung cancer
por: Chen, Shanhao, et al.
Publicado: (2020)

MicroRNA-199a-3p suppresses glioma cell proliferation by regulating the AKT/mTOR signaling pathway
por: Shen, Liang, et al.
Publicado: (2015)

LncRNA GSCAR promotes glioma stem cell maintenance via stabilizing SOX2 expression
por: Jiang, Xiulin, et al.
Publicado: (2023)

DIPG-39. New preclinical models for Diffuse Midline Glioma
por: Klenner, Marbod, et al.
Publicado: (2022)

Nucleotide Analog ARL67156 as a Lead Structure for the Development of CD39 and Dual CD39/CD73 Ectonucleotidase Inhibitors
por: Schäkel, Laura, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_nhei3ump6mp5heu5juv0i4qc5n