Rapid Generation of Ventral Spinal Cord-like Astrocytes from Human iPSCs for Modeling Non-Cell Autonomous Mechanisms of Lower Motor Neuron Disease

Astrocytes play important roles in the function and survival of neuronal cells. Dysfunctions of astrocytes are associated with numerous disorders and diseases of the nervous system, including motor neuron diseases such as amyotrophic lateral sclerosis (ALS). Human-induced pluripotent stem cell (iPSC...

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Detalles Bibliográficos
Autores principales: Soubannier, Vincent, Chaineau, Mathilde, Gursu, Lale, Haghi, Ghazal, Franco Flores, Anna Kristyna, Rouleau, Guy, Durcan, Thomas M., Stifani, Stefano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8834281/
https://www.ncbi.nlm.nih.gov/pubmed/35159209
http://dx.doi.org/10.3390/cells11030399

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