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Olfactory Dysfunction in COVID-19 Patients Who Do Not Report Olfactory Symptoms: A Pilot Study with Some Suggestions for Dentists

Background: Smell and taste dysfunction are frequently reported by SARS-CoV-2 positive patients. The degree of olfactory and gustatory dysfunction varies from a very mild reduction to their complete loss. Several studies have been performed to determine their prevalence in COVID-19 patients, mostly...

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Autores principales: Favero, Riccardo, Hajrulla, Silva, Bordin, Anna, Mucignat-Caretta, Carla, Gaudioso, Piergiorgio, Scarpa, Bruno, Favero, Lorenzo, Ottaviano, Giancarlo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8834295/
https://www.ncbi.nlm.nih.gov/pubmed/35162061
http://dx.doi.org/10.3390/ijerph19031036
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author Favero, Riccardo
Hajrulla, Silva
Bordin, Anna
Mucignat-Caretta, Carla
Gaudioso, Piergiorgio
Scarpa, Bruno
Favero, Lorenzo
Ottaviano, Giancarlo
author_facet Favero, Riccardo
Hajrulla, Silva
Bordin, Anna
Mucignat-Caretta, Carla
Gaudioso, Piergiorgio
Scarpa, Bruno
Favero, Lorenzo
Ottaviano, Giancarlo
author_sort Favero, Riccardo
collection PubMed
description Background: Smell and taste dysfunction are frequently reported by SARS-CoV-2 positive patients. The degree of olfactory and gustatory dysfunction varies from a very mild reduction to their complete loss. Several studies have been performed to determine their prevalence in COVID-19 patients, mostly using subjective measurement methods. The literature lacks long-term studies regarding duration and recovery. Methods: We assessed olfactory performance, using the Sniffin’ Sticks olfactory test, in a group of patients who had not reported olfactory dysfunction, around 131 days after their COVID-19 diagnosis. Results: 11 out of 20 subjects showed no olfactory reduction (65%), while 9 subjects showed reduced TDI score (45%). A total of 13 subjects (65%) scored above the cutoff point for Threshold, 16 subjects (80%) scored above the cutoff point for discrimination and 13 subjects (65%) scored above the cutoff point for identification. Conclusion: Objective measurement methods of olfactory performance show a higher prevalence of olfactory reduction compared to patients’ self-reported questionnaires. Olfactory dysfunction can last even months after its onset and because of its high prevalence, it could be a screening symptom for suspect COVID-19 cases.
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spelling pubmed-88342952022-02-12 Olfactory Dysfunction in COVID-19 Patients Who Do Not Report Olfactory Symptoms: A Pilot Study with Some Suggestions for Dentists Favero, Riccardo Hajrulla, Silva Bordin, Anna Mucignat-Caretta, Carla Gaudioso, Piergiorgio Scarpa, Bruno Favero, Lorenzo Ottaviano, Giancarlo Int J Environ Res Public Health Article Background: Smell and taste dysfunction are frequently reported by SARS-CoV-2 positive patients. The degree of olfactory and gustatory dysfunction varies from a very mild reduction to their complete loss. Several studies have been performed to determine their prevalence in COVID-19 patients, mostly using subjective measurement methods. The literature lacks long-term studies regarding duration and recovery. Methods: We assessed olfactory performance, using the Sniffin’ Sticks olfactory test, in a group of patients who had not reported olfactory dysfunction, around 131 days after their COVID-19 diagnosis. Results: 11 out of 20 subjects showed no olfactory reduction (65%), while 9 subjects showed reduced TDI score (45%). A total of 13 subjects (65%) scored above the cutoff point for Threshold, 16 subjects (80%) scored above the cutoff point for discrimination and 13 subjects (65%) scored above the cutoff point for identification. Conclusion: Objective measurement methods of olfactory performance show a higher prevalence of olfactory reduction compared to patients’ self-reported questionnaires. Olfactory dysfunction can last even months after its onset and because of its high prevalence, it could be a screening symptom for suspect COVID-19 cases. MDPI 2022-01-18 /pmc/articles/PMC8834295/ /pubmed/35162061 http://dx.doi.org/10.3390/ijerph19031036 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Favero, Riccardo
Hajrulla, Silva
Bordin, Anna
Mucignat-Caretta, Carla
Gaudioso, Piergiorgio
Scarpa, Bruno
Favero, Lorenzo
Ottaviano, Giancarlo
Olfactory Dysfunction in COVID-19 Patients Who Do Not Report Olfactory Symptoms: A Pilot Study with Some Suggestions for Dentists
title Olfactory Dysfunction in COVID-19 Patients Who Do Not Report Olfactory Symptoms: A Pilot Study with Some Suggestions for Dentists
title_full Olfactory Dysfunction in COVID-19 Patients Who Do Not Report Olfactory Symptoms: A Pilot Study with Some Suggestions for Dentists
title_fullStr Olfactory Dysfunction in COVID-19 Patients Who Do Not Report Olfactory Symptoms: A Pilot Study with Some Suggestions for Dentists
title_full_unstemmed Olfactory Dysfunction in COVID-19 Patients Who Do Not Report Olfactory Symptoms: A Pilot Study with Some Suggestions for Dentists
title_short Olfactory Dysfunction in COVID-19 Patients Who Do Not Report Olfactory Symptoms: A Pilot Study with Some Suggestions for Dentists
title_sort olfactory dysfunction in covid-19 patients who do not report olfactory symptoms: a pilot study with some suggestions for dentists
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8834295/
https://www.ncbi.nlm.nih.gov/pubmed/35162061
http://dx.doi.org/10.3390/ijerph19031036
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