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Polypharmacy in Polish Older Adult Population—A Cross-Sectional Study: Results of the PolSenior Project

Polypharmacy is a challenging issue in geriatrics. The aim of the study was to characterize correlates of polypharmacy in the PolSenior project. The PolSenior project, was a comprehensive survey in a large and longitudinal representative sample of thePolish older population. The project was conducte...

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Autores principales: Neumann-Podczaska, Agnieszka, Tobis, Slawomir, Antimisiaris, Demetra, Mossakowska, Malgorzata, Puzianowska-Kuznicka, Monika, Chudek, Jerzy, Wierucki, Lukasz, Merks, Piotr, Wizner, Barbara, Sobieszczanska, Malgorzata, Niemir, Zofia I., Kaczmarek, Beata, Wieczorowska-Tobis, Katarzyna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8834400/
https://www.ncbi.nlm.nih.gov/pubmed/35162054
http://dx.doi.org/10.3390/ijerph19031030
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author Neumann-Podczaska, Agnieszka
Tobis, Slawomir
Antimisiaris, Demetra
Mossakowska, Malgorzata
Puzianowska-Kuznicka, Monika
Chudek, Jerzy
Wierucki, Lukasz
Merks, Piotr
Wizner, Barbara
Sobieszczanska, Malgorzata
Niemir, Zofia I.
Kaczmarek, Beata
Wieczorowska-Tobis, Katarzyna
author_facet Neumann-Podczaska, Agnieszka
Tobis, Slawomir
Antimisiaris, Demetra
Mossakowska, Malgorzata
Puzianowska-Kuznicka, Monika
Chudek, Jerzy
Wierucki, Lukasz
Merks, Piotr
Wizner, Barbara
Sobieszczanska, Malgorzata
Niemir, Zofia I.
Kaczmarek, Beata
Wieczorowska-Tobis, Katarzyna
author_sort Neumann-Podczaska, Agnieszka
collection PubMed
description Polypharmacy is a challenging issue in geriatrics. The aim of the study was to characterize correlates of polypharmacy in the PolSenior project. The PolSenior project, was a comprehensive survey in a large and longitudinal representative sample of thePolish older population. The project was conducted by the International Institute of Molecular and Cell Biology in Warsaw between 2008 and 2011. All medications consumed during the week preceding the survey were evaluated for each participant (n = 4793, including 2314 females (48.3%)). Thereafter, the percentage of those with polypharmacy (at least 5 medications) and excessive polypharmacy (at least 10 medications) was calculated, and their correlates were determined. The average number of medications used by participants was 5.1 ± 3.6, and was higher in females than in males (5.5 ± 3.5 vs. 4.8 ± 3.5; p < 0.001). Polypharmacy characterized 2650 participants (55.3%) and excessive polypharmacy—532 of them (11.1%). The independent correlates associated withpolypharmacy were: age over 70 years, female sex, higher than primary education, living in an urban area, comorbidities, any hospitalization during past five years, and visiting general practicioners at least yearly. As for correlates with excessive polypharmacy, they were: age 80–84 years, female sex, living in an urban area, diagnosis of at least four chronic diseases, and at least two hospitalizations in the last five years. This study serves as a starting place to understand patient characteristics associated with polypharmacy, excessive polypharmacy, and identify targeted interventions.
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spelling pubmed-88344002022-02-12 Polypharmacy in Polish Older Adult Population—A Cross-Sectional Study: Results of the PolSenior Project Neumann-Podczaska, Agnieszka Tobis, Slawomir Antimisiaris, Demetra Mossakowska, Malgorzata Puzianowska-Kuznicka, Monika Chudek, Jerzy Wierucki, Lukasz Merks, Piotr Wizner, Barbara Sobieszczanska, Malgorzata Niemir, Zofia I. Kaczmarek, Beata Wieczorowska-Tobis, Katarzyna Int J Environ Res Public Health Article Polypharmacy is a challenging issue in geriatrics. The aim of the study was to characterize correlates of polypharmacy in the PolSenior project. The PolSenior project, was a comprehensive survey in a large and longitudinal representative sample of thePolish older population. The project was conducted by the International Institute of Molecular and Cell Biology in Warsaw between 2008 and 2011. All medications consumed during the week preceding the survey were evaluated for each participant (n = 4793, including 2314 females (48.3%)). Thereafter, the percentage of those with polypharmacy (at least 5 medications) and excessive polypharmacy (at least 10 medications) was calculated, and their correlates were determined. The average number of medications used by participants was 5.1 ± 3.6, and was higher in females than in males (5.5 ± 3.5 vs. 4.8 ± 3.5; p < 0.001). Polypharmacy characterized 2650 participants (55.3%) and excessive polypharmacy—532 of them (11.1%). The independent correlates associated withpolypharmacy were: age over 70 years, female sex, higher than primary education, living in an urban area, comorbidities, any hospitalization during past five years, and visiting general practicioners at least yearly. As for correlates with excessive polypharmacy, they were: age 80–84 years, female sex, living in an urban area, diagnosis of at least four chronic diseases, and at least two hospitalizations in the last five years. This study serves as a starting place to understand patient characteristics associated with polypharmacy, excessive polypharmacy, and identify targeted interventions. MDPI 2022-01-18 /pmc/articles/PMC8834400/ /pubmed/35162054 http://dx.doi.org/10.3390/ijerph19031030 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Neumann-Podczaska, Agnieszka
Tobis, Slawomir
Antimisiaris, Demetra
Mossakowska, Malgorzata
Puzianowska-Kuznicka, Monika
Chudek, Jerzy
Wierucki, Lukasz
Merks, Piotr
Wizner, Barbara
Sobieszczanska, Malgorzata
Niemir, Zofia I.
Kaczmarek, Beata
Wieczorowska-Tobis, Katarzyna
Polypharmacy in Polish Older Adult Population—A Cross-Sectional Study: Results of the PolSenior Project
title Polypharmacy in Polish Older Adult Population—A Cross-Sectional Study: Results of the PolSenior Project
title_full Polypharmacy in Polish Older Adult Population—A Cross-Sectional Study: Results of the PolSenior Project
title_fullStr Polypharmacy in Polish Older Adult Population—A Cross-Sectional Study: Results of the PolSenior Project
title_full_unstemmed Polypharmacy in Polish Older Adult Population—A Cross-Sectional Study: Results of the PolSenior Project
title_short Polypharmacy in Polish Older Adult Population—A Cross-Sectional Study: Results of the PolSenior Project
title_sort polypharmacy in polish older adult population—a cross-sectional study: results of the polsenior project
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8834400/
https://www.ncbi.nlm.nih.gov/pubmed/35162054
http://dx.doi.org/10.3390/ijerph19031030
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