Telomerase in Cancer: Function, Regulation, and Clinical Translation

SIMPLE SUMMARY: Cells undergoing malignant transformation must circumvent replicative senescence and eventual cell death associated with progressive telomere shortening that occurs through successive cell division. To do so, malignant cells reactivate telomerase to extend their telomeres and achieve...

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Detalles Bibliográficos
Autores principales: Robinson, Nathaniel J., Schiemann, William P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8834434/
https://www.ncbi.nlm.nih.gov/pubmed/35159075
http://dx.doi.org/10.3390/cancers14030808

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