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Valproic Acid-Induced CCN1 Promotes Osteogenic Differentiation by Increasing CCN1 Protein Stability through HDAC1 Inhibition in Tonsil-Derived Mesenchymal Stem Cells

Our previous study found that the level of CCN1 increases as osteogenic differentiation progresses in tonsil-derived mesenchymal stem cells (TMSCs). This study investigated how CCN1 is regulated through HDAC inhibition in TMSCs and their relationship with osteogenesis. Valproic acid (VPA) (1–5 mM),...

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Detalles Bibliográficos
Autores principales:	Yu, Yeonsil, Oh, Se-Young, Kim, Ha Yeong, Choi, Ji-Young, Jo, Sangmee Ahn, Jo, Inho
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8834451/ https://www.ncbi.nlm.nih.gov/pubmed/35159343 http://dx.doi.org/10.3390/cells11030534

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