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Current Status and Challenges of Human Induced Pluripotent Stem Cell-Derived Liver Models in Drug Discovery

The pharmaceutical industry is in high need of efficient and relevant in vitro liver models, which can be incorporated in their drug discovery pipelines to identify potential drugs and their toxicity profiles. Current liver models often rely on cancer cell lines or primary cells, which both have maj...

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Detalles Bibliográficos
Autores principales: Tricot, Tine, Verfaillie, Catherine M., Kumar, Manoj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8834601/
https://www.ncbi.nlm.nih.gov/pubmed/35159250
http://dx.doi.org/10.3390/cells11030442

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