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BMP9 Promotes an Epithelial Phenotype and a Hepatocyte-like Gene Expression Profile in Adult Hepatic Progenitor Cells

Bone morphogenetic protein 9 (BMP9), a member of the TGF-β superfamily, has emerged as a new player in chronic liver diseases (CLDs). Its levels increase in the fibrotic liver where it promotes fibrogenesis. It also regulates hepatic progenitor cells (oval cells in rodents), a cell population that c...

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Detalles Bibliográficos
Autores principales: Addante, Annalisa, González-Corralejo, Carlos, Roncero, Cesáreo, Lazcanoiturburu, Nerea, García-Sáez, Juan, Herrera, Blanca, Sánchez, Aránzazu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8834621/
https://www.ncbi.nlm.nih.gov/pubmed/35159174
http://dx.doi.org/10.3390/cells11030365