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What Have We Learned in 30 Years of Investigations on Bari Transposons?

Transposable elements (TEs) have been historically depicted as detrimental genetic entities that selfishly aim at perpetuating themselves, invading genomes, and destroying genes. Scientists often co-opt “special” TEs to develop new and powerful genetic tools, that will hopefully aid in changing the...

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Autores principales: Palazzo, Antonio, Caizzi, Ruggiero, Moschetti, Roberta, Marsano, René Massimiliano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8834629/
https://www.ncbi.nlm.nih.gov/pubmed/35159391
http://dx.doi.org/10.3390/cells11030583
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author Palazzo, Antonio
Caizzi, Ruggiero
Moschetti, Roberta
Marsano, René Massimiliano
author_facet Palazzo, Antonio
Caizzi, Ruggiero
Moschetti, Roberta
Marsano, René Massimiliano
author_sort Palazzo, Antonio
collection PubMed
description Transposable elements (TEs) have been historically depicted as detrimental genetic entities that selfishly aim at perpetuating themselves, invading genomes, and destroying genes. Scientists often co-opt “special” TEs to develop new and powerful genetic tools, that will hopefully aid in changing the future of the human being. However, many TEs are gentle, rarely unleash themselves to harm the genome, and bashfully contribute to generating diversity and novelty in the genomes they have colonized, yet they offer the opportunity to develop new molecular tools. In this review we summarize 30 years of research focused on the Bari transposons. Bari is a “normal” transposon family that has colonized the genomes of several Drosophila species and introduced genomic novelties in the melanogaster species. We discuss how these results have contributed to advance the field of TE research and what future studies can still add to the current knowledge.
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spelling pubmed-88346292022-02-12 What Have We Learned in 30 Years of Investigations on Bari Transposons? Palazzo, Antonio Caizzi, Ruggiero Moschetti, Roberta Marsano, René Massimiliano Cells Review Transposable elements (TEs) have been historically depicted as detrimental genetic entities that selfishly aim at perpetuating themselves, invading genomes, and destroying genes. Scientists often co-opt “special” TEs to develop new and powerful genetic tools, that will hopefully aid in changing the future of the human being. However, many TEs are gentle, rarely unleash themselves to harm the genome, and bashfully contribute to generating diversity and novelty in the genomes they have colonized, yet they offer the opportunity to develop new molecular tools. In this review we summarize 30 years of research focused on the Bari transposons. Bari is a “normal” transposon family that has colonized the genomes of several Drosophila species and introduced genomic novelties in the melanogaster species. We discuss how these results have contributed to advance the field of TE research and what future studies can still add to the current knowledge. MDPI 2022-02-08 /pmc/articles/PMC8834629/ /pubmed/35159391 http://dx.doi.org/10.3390/cells11030583 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Palazzo, Antonio
Caizzi, Ruggiero
Moschetti, Roberta
Marsano, René Massimiliano
What Have We Learned in 30 Years of Investigations on Bari Transposons?
title What Have We Learned in 30 Years of Investigations on Bari Transposons?
title_full What Have We Learned in 30 Years of Investigations on Bari Transposons?
title_fullStr What Have We Learned in 30 Years of Investigations on Bari Transposons?
title_full_unstemmed What Have We Learned in 30 Years of Investigations on Bari Transposons?
title_short What Have We Learned in 30 Years of Investigations on Bari Transposons?
title_sort what have we learned in 30 years of investigations on bari transposons?
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8834629/
https://www.ncbi.nlm.nih.gov/pubmed/35159391
http://dx.doi.org/10.3390/cells11030583
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