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Dysregulated PI3K Signaling in B Cells of CVID Patients

The altered wiring of signaling pathways downstream of antigen receptors of T and B cells contributes to the dysregulation of the adaptive immune system, potentially causing immunodeficiency and autoimmunity. In humans, the investigation of such complex systems benefits from nature’s experiments in...

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Detalles Bibliográficos
Autores principales: Harder, Ina, Münchhalfen, Matthias, Andrieux, Geoffroy, Boerries, Melanie, Grimbacher, Bodo, Eibel, Hermann, Maccari, Maria Elena, Ehl, Stephan, Wienands, Jürgen, Jellusova, Julia, Warnatz, Klaus, Keller, Baerbel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8834633/
https://www.ncbi.nlm.nih.gov/pubmed/35159274
http://dx.doi.org/10.3390/cells11030464

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