Cargando…

Functional Characterization of an In-Frame Deletion in the Basic Domain of the Retinal Transcription Factor ATOH7

Basic helix–loop–helix (bHLH) transcription factors are evolutionarily conserved and structurally similar proteins important in development. The temporospatial expression of atonal bHLH transcription factor 7 (ATOH7) directs the differentiation of retinal ganglion cells and mutations in the human ge...

Descripción completa

Detalles Bibliográficos
Autores principales:	Atac, David, Mohn, Lucas, Feil, Silke, Maggi, Kevin, Haenni, Dominik, Seebauer, Britta, Koller, Samuel, Berger, Wolfgang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8834682/ https://www.ncbi.nlm.nih.gov/pubmed/35162975 http://dx.doi.org/10.3390/ijms23031053

Ejemplares similares

Differential responsiveness of distinct retinal domains to Atoh7
por: Sinn, Rebecca, et al.
Publicado: (2014)

Deletion of a remote enhancer near ATOH7 disrupts retinal neurogenesis, causing NCRNA disease
por: Ghiasvand, Noor M., et al.
Publicado: (2011)

Functional Analysis of a Novel, Non-Canonical RPGR Splice Variant Causing X-Linked Retinitis Pigmentosa
por: Koller, Samuel, et al.
Publicado: (2023)

Targeted deletion of Atoh8 results in severe hearing loss in mice
por: Tang, Qi, et al.
Publicado: (2021)

Long-Range PCR-Based NGS Applications to Diagnose Mendelian Retinal Diseases
por: Maggi, Jordi, et al.
Publicado: (2021)

Atoh7-independent specification of retinal ganglion cell identity
por: Brodie-Kommit, Justin, et al.
Publicado: (2021)

Atoh8 in Development and Disease
por: Divvela, Satya Srirama Karthik, et al.
Publicado: (2022)

Integrin-linked kinase controls retinal angiogenesis and is linked to Wnt signaling and exudative vitreoretinopathy
por: Park, Hongryeol, et al.
Publicado: (2019)

Independently specified Atoh1 domains define novel developmental compartments in rhombomere 1
por: Green, Mary J., et al.
Publicado: (2014)

Notch signalling patterns retinal composition by regulating atoh7 during post-embryonic growth
por: Pérez Saturnino, Alicia, et al.
Publicado: (2018)

The Atoh7 remote enhancer provides transcriptional robustness during retinal ganglion cell development
por: Miesfeld, Joel B., et al.
Publicado: (2020)

Exome Sequencing in a Swiss Childhood Glaucoma Cohort Reveals CYP1B1 and FOXC1 Variants as Most Frequent Causes
por: Lang, Elena, et al.
Publicado: (2020)

The Basics book of frame relay
Publicado: (1993)

The Role of Atoh1 in Mucous Cell Metaplasia
por: Nakamura, Yoshihisa, et al.
Publicado: (2012)

Atoh7 promotes the differentiation of retinal stem cells derived from Müller cells into retinal ganglion cells by inhibiting Notch signaling
por: Song, Wei-tao, et al.
Publicado: (2013)

FrameMaker 6: beyond the basics
por: Jahred, Lisa
Publicado: (2002)

Transcriptome analysis of the zebrafish atoh7−/− Mutant, lakritz, highlights Atoh7‐dependent genetic networks with potential implications for human eye diseases
por: Covello, Giuseppina, et al.
Publicado: (2020)

Single cell transcriptomics reveals lineage trajectory of retinal ganglion cells in wild-type and Atoh7-null retinas
por: Wu, Fuguo, et al.
Publicado: (2021)

Whole Exome Sequencing in Coloboma/Microphthalmia: Identification of Novel and Recurrent Variants in Seven Genes
por: Haug, Patricia, et al.
Publicado: (2021)

Deletion of Jdp2 enhances Slc7a11 expression in Atoh-1 positive cerebellum granule cell progenitors in vivo
por: Ku, Chia-Chen, et al.
Publicado: (2021)

A Novel Atoh1 “Self-Terminating” Mouse Model Reveals the Necessity of Proper Atoh1 Level and Duration for Hair Cell Differentiation and Viability
por: Pan, Ning, et al.
Publicado: (2012)

Transcriptional Regulation by ATOH1 and its Target SPDEF in the Intestine
por: Lo, Yuan-Hung, et al.
Publicado: (2016)

Zebrafish atoh8 mutants do not recapitulate morpholino phenotypes
por: Place, Elsie S., et al.
Publicado: (2017)

Regulation of Gliogenesis by lin-32/Atoh1 in Caenorhabditis elegans
por: Zhang, Albert, et al.
Publicado: (2020)

atoh8 expression pattern in early zebrafish embryonic development
por: Fragale, Ninfa, et al.
Publicado: (2021)

Long-term consequences of developmental vascular defects on retinal vessel homeostasis and function in a mouse model of Norrie disease
por: Beck, Susanne C., et al.
Publicado: (2017)

Functional Polymorphisms in Dopaminergic Genes Modulate Neurobehavioral and Neurophysiological Consequences of Sleep Deprivation
por: Holst, Sebastian C., et al.
Publicado: (2017)

Lentivirus carrying the Atoh1 gene infects normal rat cochlea
por: Pan, Song, et al.
Publicado: (2013)

ATOH8, a regulator of skeletal myogenesis in the hypaxial myotome of the trunk
por: Balakrishnan-Renuka, Ajeesh, et al.
Publicado: (2013)

A novel interaction between ATOH8 and PPP3CB
por: Chen, Jingchen, et al.
Publicado: (2015)

Jak2-mediated phosphorylation of Atoh1 is critical for medulloblastoma growth
por: Klisch, Tiemo J, et al.
Publicado: (2017)

The Repression of Atoh1 by Neurogenin1 during Inner Ear Development
por: Gálvez, Héctor, et al.
Publicado: (2017)

Contribution of ATOH1(+) Cells to the Homeostasis, Repair, and Tumorigenesis of the Colonic Epithelium
por: Ishibashi, Fumiaki, et al.
Publicado: (2017)

Rbpj direct regulation of Atoh7 transcription in the embryonic mouse retina
por: Miesfeld, Joel B., et al.
Publicado: (2018)

Correction: Zebrafish atoh8 mutants do not recapitulate morpholino phenotypes
por: Place, Elsie S., et al.
Publicado: (2017)

Atoh1 drives the heterogeneity of the pontine nuclei neurons and promotes their differentiation
por: Wu, Sih-Rong, et al.
Publicado: (2023)

Identification of genes concordantly expressed with Atoh1 during inner ear development
por: Yoon, Heejei, et al.
Publicado: (2011)

Atoh1 as a Coordinator of Sensory Hair Cell Development and Regeneration in the Cochlea
por: Lee, Sungsu, et al.
Publicado: (2017)

De novo neurogenesis by targeted expression of atoh7 to Müller glia cells
por: Lust, Katharina, et al.
Publicado: (2016)

Phospho-regulation of ATOH1 Is Required for Plasticity of Secretory Progenitors and Tissue Regeneration
por: Tomic, Goran, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_d1tqkrucpuubk3or1ak6fg6j9v