CRISPR Editing Enables Consequential Tag-Activated MicroRNA-Mediated Endogene Deactivation

Molecular therapies and functional studies greatly benefit from spatial and temporal precision of genetic intervention. We therefore conceived and explored tag-activated microRNA (miRNA)-mediated endogene deactivation (TAMED) as a research tool and potential lineage-specific therapy. For proof of pr...

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Detalles Bibliográficos
Autores principales: Papasavva, Panayiota L., Patsali, Petros, Loucari, Constantinos C., Kurita, Ryo, Nakamura, Yukio, Kleanthous, Marina, Lederer, Carsten W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8834719/
https://www.ncbi.nlm.nih.gov/pubmed/35163006
http://dx.doi.org/10.3390/ijms23031082

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