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Protein Disulfide Isomerase A3 Regulates Influenza Neuraminidase Activity and Influenza Burden in the Lung

Influenza (IAV) neuraminidase (NA) is a glycoprotein required for the viral exit from the cell. NA requires disulfide bonds for proper function. We have recently demonstrated that protein disulfide isomerase (PDI)A3 is required for oxidative folding of IAV hemagglutinin (HA), and viral propagation....

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Detalles Bibliográficos
Autores principales: Chamberlain, Nicolas, Ruban, Mona, Mark, Zoe F., Bruno, Sierra R., Kumar, Amit, Chandrasekaran, Ravishankar, Souza De Lima, Dhemerson, Antos, Danielle, Nakada, Emily M., Alcorn, John F., Anathy, Vikas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8834910/
https://www.ncbi.nlm.nih.gov/pubmed/35162999
http://dx.doi.org/10.3390/ijms23031078