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Chemotherapeutics Combined with Luminal Irritants: Effects on Small-Intestinal Mannitol Permeability and Villus Length in Rats
Chemotherapy causes intestinal mucositis, which includes villous atrophy and altered mucosal barrier function. However, there is an uncertainty regarding how the reduced small-intestinal surface area affects the mucosal permeability of the small marker probe mannitol (MW 188), and how the mucosa res...
Autores principales: | Cano-Cebrián, Maria-José, Dahlgren, David, Kullenberg, Fredrik, Peters, Karsten, Olander, Tobias, Sjöblom, Markus, Lennernäs, Hans |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8834916/ https://www.ncbi.nlm.nih.gov/pubmed/35162944 http://dx.doi.org/10.3390/ijms23031021 |
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