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The Diagnostic Accuracy and Clinimetric Properties of Screening Instruments to Identify Frail Older Adults Attending Emergency Departments: A Protocol for a Mixed Methods Systematic Review and Meta-Analysis

Background: Prompt and efficient identification and stratification of patients who are frail is important, as this cohort are at high risk of adverse healthcare outcomes. Numerous frailty screening tools have been developed to support their identification across different settings, yet relatively fe...

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Autores principales: Moloney, Elizabeth, Sezgin, Duygu, O’Donovan, Mark, Adja, Kadjo Yves Cedric, McGrath, Keith, Liew, Aaron, Lenzi, Jacopo, Gori, Davide, O’Connor, Kieran, Molloy, David William, Flanagan, Evelyn, McLoughlin, Darren, Fantini, Maria Pia, Timmons, Suzanne, O’Caoimh, Rónán
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8834939/
https://www.ncbi.nlm.nih.gov/pubmed/35162397
http://dx.doi.org/10.3390/ijerph19031380
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author Moloney, Elizabeth
Sezgin, Duygu
O’Donovan, Mark
Adja, Kadjo Yves Cedric
McGrath, Keith
Liew, Aaron
Lenzi, Jacopo
Gori, Davide
O’Connor, Kieran
Molloy, David William
Flanagan, Evelyn
McLoughlin, Darren
Fantini, Maria Pia
Timmons, Suzanne
O’Caoimh, Rónán
author_facet Moloney, Elizabeth
Sezgin, Duygu
O’Donovan, Mark
Adja, Kadjo Yves Cedric
McGrath, Keith
Liew, Aaron
Lenzi, Jacopo
Gori, Davide
O’Connor, Kieran
Molloy, David William
Flanagan, Evelyn
McLoughlin, Darren
Fantini, Maria Pia
Timmons, Suzanne
O’Caoimh, Rónán
author_sort Moloney, Elizabeth
collection PubMed
description Background: Prompt and efficient identification and stratification of patients who are frail is important, as this cohort are at high risk of adverse healthcare outcomes. Numerous frailty screening tools have been developed to support their identification across different settings, yet relatively few have emerged for use in emergency departments (EDs). This protocol provides details for a systematic review aiming to synthesize the accumulated evidence regarding the diagnostic accuracy and clinimetric properties of frailty screening instruments to identify frail older adults in EDs. Methods: Six electronic databases will be searched from January 2000 to March 2021. Eligible studies will include adults aged ≥60 years screened in EDs with any available screening instrument to identify frailty (even if not originally designed for this purpose). Studies, including case-control, longitudinal, and cohort studies, will be included, where instruments are compared to a reference standard to explore diagnostic accuracy. Predictive accuracy for a selection of outcomes, including mortality, institutionalization, and readmission, will be assessed. Clinical and methodological heterogeneity will be examined, and a random effects meta-analysis performed if appropriate. Conclusion: Understanding whether frailty screening on presentation to EDs is accurate in identifying frailty, and predicting these outcomes is important for decision-making and targeting appropriate management.
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spelling pubmed-88349392022-02-12 The Diagnostic Accuracy and Clinimetric Properties of Screening Instruments to Identify Frail Older Adults Attending Emergency Departments: A Protocol for a Mixed Methods Systematic Review and Meta-Analysis Moloney, Elizabeth Sezgin, Duygu O’Donovan, Mark Adja, Kadjo Yves Cedric McGrath, Keith Liew, Aaron Lenzi, Jacopo Gori, Davide O’Connor, Kieran Molloy, David William Flanagan, Evelyn McLoughlin, Darren Fantini, Maria Pia Timmons, Suzanne O’Caoimh, Rónán Int J Environ Res Public Health Study Protocol Background: Prompt and efficient identification and stratification of patients who are frail is important, as this cohort are at high risk of adverse healthcare outcomes. Numerous frailty screening tools have been developed to support their identification across different settings, yet relatively few have emerged for use in emergency departments (EDs). This protocol provides details for a systematic review aiming to synthesize the accumulated evidence regarding the diagnostic accuracy and clinimetric properties of frailty screening instruments to identify frail older adults in EDs. Methods: Six electronic databases will be searched from January 2000 to March 2021. Eligible studies will include adults aged ≥60 years screened in EDs with any available screening instrument to identify frailty (even if not originally designed for this purpose). Studies, including case-control, longitudinal, and cohort studies, will be included, where instruments are compared to a reference standard to explore diagnostic accuracy. Predictive accuracy for a selection of outcomes, including mortality, institutionalization, and readmission, will be assessed. Clinical and methodological heterogeneity will be examined, and a random effects meta-analysis performed if appropriate. Conclusion: Understanding whether frailty screening on presentation to EDs is accurate in identifying frailty, and predicting these outcomes is important for decision-making and targeting appropriate management. MDPI 2022-01-26 /pmc/articles/PMC8834939/ /pubmed/35162397 http://dx.doi.org/10.3390/ijerph19031380 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Study Protocol
Moloney, Elizabeth
Sezgin, Duygu
O’Donovan, Mark
Adja, Kadjo Yves Cedric
McGrath, Keith
Liew, Aaron
Lenzi, Jacopo
Gori, Davide
O’Connor, Kieran
Molloy, David William
Flanagan, Evelyn
McLoughlin, Darren
Fantini, Maria Pia
Timmons, Suzanne
O’Caoimh, Rónán
The Diagnostic Accuracy and Clinimetric Properties of Screening Instruments to Identify Frail Older Adults Attending Emergency Departments: A Protocol for a Mixed Methods Systematic Review and Meta-Analysis
title The Diagnostic Accuracy and Clinimetric Properties of Screening Instruments to Identify Frail Older Adults Attending Emergency Departments: A Protocol for a Mixed Methods Systematic Review and Meta-Analysis
title_full The Diagnostic Accuracy and Clinimetric Properties of Screening Instruments to Identify Frail Older Adults Attending Emergency Departments: A Protocol for a Mixed Methods Systematic Review and Meta-Analysis
title_fullStr The Diagnostic Accuracy and Clinimetric Properties of Screening Instruments to Identify Frail Older Adults Attending Emergency Departments: A Protocol for a Mixed Methods Systematic Review and Meta-Analysis
title_full_unstemmed The Diagnostic Accuracy and Clinimetric Properties of Screening Instruments to Identify Frail Older Adults Attending Emergency Departments: A Protocol for a Mixed Methods Systematic Review and Meta-Analysis
title_short The Diagnostic Accuracy and Clinimetric Properties of Screening Instruments to Identify Frail Older Adults Attending Emergency Departments: A Protocol for a Mixed Methods Systematic Review and Meta-Analysis
title_sort diagnostic accuracy and clinimetric properties of screening instruments to identify frail older adults attending emergency departments: a protocol for a mixed methods systematic review and meta-analysis
topic Study Protocol
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8834939/
https://www.ncbi.nlm.nih.gov/pubmed/35162397
http://dx.doi.org/10.3390/ijerph19031380
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