Paclitaxel-Induced Epidermal Alterations: An In Vitro Preclinical Assessment in Primary Keratinocytes and in a 3D Epidermis Model

Paclitaxel is a microtubule-stabilizing chemotherapeutic agent approved for the treatment of ovarian, non-small cell lung, head, neck, and breast cancers. Despite its beneficial effects on cancer and widespread use, paclitaxel also damages healthy tissues, including the skin. However, the mechanisms...

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Detalles Bibliográficos
Autores principales: Montero, Paula, Milara, Javier, Pérez-Leal, Martín, Estornut, Cristina, Roger, Inés, Pérez-Fidalgo, Alejandro, Sanz, Celia, Cortijo, Julio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8834980/
https://www.ncbi.nlm.nih.gov/pubmed/35163066
http://dx.doi.org/10.3390/ijms23031142

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8834980/
https://www.ncbi.nlm.nih.gov/pubmed/35163066
http://dx.doi.org/10.3390/ijms23031142

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