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Paclitaxel-Induced Epidermal Alterations: An In Vitro Preclinical Assessment in Primary Keratinocytes and in a 3D Epidermis Model
Paclitaxel is a microtubule-stabilizing chemotherapeutic agent approved for the treatment of ovarian, non-small cell lung, head, neck, and breast cancers. Despite its beneficial effects on cancer and widespread use, paclitaxel also damages healthy tissues, including the skin. However, the mechanisms...
Autores principales: | Montero, Paula, Milara, Javier, Pérez-Leal, Martín, Estornut, Cristina, Roger, Inés, Pérez-Fidalgo, Alejandro, Sanz, Celia, Cortijo, Julio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8834980/ https://www.ncbi.nlm.nih.gov/pubmed/35163066 http://dx.doi.org/10.3390/ijms23031142 |
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