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Non-Invasive Assessment of Locally Overexpressed Human Adenosine 2A Receptors in the Heart of Transgenic Mice

A(2A) adenosine receptors (A(2A)-AR) have a cardio-protective function upon ischemia and reperfusion, but on the other hand, their stimulation could lead to arrhythmias. Our aim was to investigate the potential use of the PET radiotracer [(18)F]FLUDA to non-invasively determine the A(2A)-AR availabi...

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Detalles Bibliográficos
Autores principales: Gündel, Daniel, Lai, Thu Hang, Dukic-Stefanovic, Sladjana, Teodoro, Rodrigo, Deuther-Conrad, Winnie, Toussaint, Magali, Kopka, Klaus, Moldovan, Rareş-Petru, Boknik, Peter, Hofmann, Britt, Gergs, Ulrich, Neumann, Joachim, Brust, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8835051/
https://www.ncbi.nlm.nih.gov/pubmed/35162950
http://dx.doi.org/10.3390/ijms23031025