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Reduction in Ventilation-Induced Diaphragmatic Mitochondrial Injury through Hypoxia-Inducible Factor 1α in a Murine Endotoxemia Model

Mechanical ventilation (MV) is essential for patients with sepsis-related respiratory failure but can cause ventilator-induced diaphragm dysfunction (VIDD), which involves diaphragmatic myofiber atrophy and contractile inactivity. Mitochondrial DNA, oxidative stress, mitochondrial dynamics, and biog...

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Detalles Bibliográficos
Autores principales: Li, Li-Fu, Yu, Chung-Chieh, Wu, Huang-Pin, Chu, Chien-Ming, Huang, Chih-Yu, Liu, Ping-Chi, Liu, Yung-Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8835058/
https://www.ncbi.nlm.nih.gov/pubmed/35163007
http://dx.doi.org/10.3390/ijms23031083

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