Ibuprofen, Flurbiprofen, Etoricoxib or Paracetamol Do Not Influence ACE2 Expression and Activity In Vitro or in Mice and Do Not Exacerbate In-Vitro SARS-CoV-2 Infection

SARS-CoV-2 uses the human cell surface protein angiotensin converting enzyme 2 (ACE2) as the receptor by which it gains access into lung and other tissue. Early in the pandemic, there was speculation that a number of commonly used medications—including ibuprofen and other non-steroidal anti-inflamma...

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Detalles Bibliográficos
Autores principales: de Bruin, Natasja, Schneider, Ann-Kathrin, Reus, Philipp, Talmon, Sonja, Ciesek, Sandra, Bojkova, Denisa, Cinatl, Jindrich, Lodhi, Imran, Charlesworth, Bruce, Sinclair, Simon, Pennick, Graham, Laughey, William F., Gribbon, Philip, Kannt, Aimo, Schiffmann, Susanne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8835123/
https://www.ncbi.nlm.nih.gov/pubmed/35162972
http://dx.doi.org/10.3390/ijms23031049

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