Cysteine 467 of the ASCT2 Amino Acid Transporter Is a Molecular Determinant of the Antiport Mechanism

The plasma membrane transporter ASCT2 is a well-known Na(+)-dependent obligatory antiporter of neutral amino acids. The crucial role of the residue C467 in the recognition and binding of the ASCT2 substrate glutamine, has been highlighted by structure/function relationship studies. The reconstitutio...

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Detalles Bibliográficos
Autores principales: Scalise, Mariafrancesca, Pappacoda, Gilda, Mazza, Tiziano, Console, Lara, Pochini, Lorena, Indiveri, Cesare
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8835248/
https://www.ncbi.nlm.nih.gov/pubmed/35163050
http://dx.doi.org/10.3390/ijms23031127

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8835248/
https://www.ncbi.nlm.nih.gov/pubmed/35163050
http://dx.doi.org/10.3390/ijms23031127

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