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Uncovering Evidence: Associations between Environmental Contaminants and Disparities in Women’s Health

Over the years, industrial accidents and military actions have led to unintentional, large-scale, high-dose human exposure to environmental contaminants with endocrine-disrupting action. These historical events, in addition to laboratory studies, suggest that exposure to toxicants such as dioxins an...

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Autores principales: Rumph, Jelonia T., Stephens, Victoria R., Martin, Joanie L., Brown, LaKendria K., Thomas, Portia L., Cooley, Ayorinde, Osteen, Kevin G., Bruner-Tran, Kaylon L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8835285/
https://www.ncbi.nlm.nih.gov/pubmed/35162279
http://dx.doi.org/10.3390/ijerph19031257
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author Rumph, Jelonia T.
Stephens, Victoria R.
Martin, Joanie L.
Brown, LaKendria K.
Thomas, Portia L.
Cooley, Ayorinde
Osteen, Kevin G.
Bruner-Tran, Kaylon L.
author_facet Rumph, Jelonia T.
Stephens, Victoria R.
Martin, Joanie L.
Brown, LaKendria K.
Thomas, Portia L.
Cooley, Ayorinde
Osteen, Kevin G.
Bruner-Tran, Kaylon L.
author_sort Rumph, Jelonia T.
collection PubMed
description Over the years, industrial accidents and military actions have led to unintentional, large-scale, high-dose human exposure to environmental contaminants with endocrine-disrupting action. These historical events, in addition to laboratory studies, suggest that exposure to toxicants such as dioxins and polychlorinated biphenyls negatively impact the reproductive system and likely influence the development of gynecologic diseases. Although high-level exposure to a single toxicant is rare, humans living in industrialized countries are continuously exposed to a complex mixture of manmade and naturally produced endocrine disruptors, including persistent organic pollutants and heavy metals. Since minorities are more likely to live in areas with known environmental contamination; herein, we conducted a literature review to identify potential associations between toxicant exposure and racial disparities in women’s health. Evidence within the literature suggests that the body burden of environmental contaminants, especially in combination with inherent genetic variations, likely contributes to previously observed racial disparities in women’s health conditions such as breast cancer, endometriosis, polycystic ovarian syndrome, uterine fibroids, and premature birth.
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spelling pubmed-88352852022-02-12 Uncovering Evidence: Associations between Environmental Contaminants and Disparities in Women’s Health Rumph, Jelonia T. Stephens, Victoria R. Martin, Joanie L. Brown, LaKendria K. Thomas, Portia L. Cooley, Ayorinde Osteen, Kevin G. Bruner-Tran, Kaylon L. Int J Environ Res Public Health Review Over the years, industrial accidents and military actions have led to unintentional, large-scale, high-dose human exposure to environmental contaminants with endocrine-disrupting action. These historical events, in addition to laboratory studies, suggest that exposure to toxicants such as dioxins and polychlorinated biphenyls negatively impact the reproductive system and likely influence the development of gynecologic diseases. Although high-level exposure to a single toxicant is rare, humans living in industrialized countries are continuously exposed to a complex mixture of manmade and naturally produced endocrine disruptors, including persistent organic pollutants and heavy metals. Since minorities are more likely to live in areas with known environmental contamination; herein, we conducted a literature review to identify potential associations between toxicant exposure and racial disparities in women’s health. Evidence within the literature suggests that the body burden of environmental contaminants, especially in combination with inherent genetic variations, likely contributes to previously observed racial disparities in women’s health conditions such as breast cancer, endometriosis, polycystic ovarian syndrome, uterine fibroids, and premature birth. MDPI 2022-01-23 /pmc/articles/PMC8835285/ /pubmed/35162279 http://dx.doi.org/10.3390/ijerph19031257 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Rumph, Jelonia T.
Stephens, Victoria R.
Martin, Joanie L.
Brown, LaKendria K.
Thomas, Portia L.
Cooley, Ayorinde
Osteen, Kevin G.
Bruner-Tran, Kaylon L.
Uncovering Evidence: Associations between Environmental Contaminants and Disparities in Women’s Health
title Uncovering Evidence: Associations between Environmental Contaminants and Disparities in Women’s Health
title_full Uncovering Evidence: Associations between Environmental Contaminants and Disparities in Women’s Health
title_fullStr Uncovering Evidence: Associations between Environmental Contaminants and Disparities in Women’s Health
title_full_unstemmed Uncovering Evidence: Associations between Environmental Contaminants and Disparities in Women’s Health
title_short Uncovering Evidence: Associations between Environmental Contaminants and Disparities in Women’s Health
title_sort uncovering evidence: associations between environmental contaminants and disparities in women’s health
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8835285/
https://www.ncbi.nlm.nih.gov/pubmed/35162279
http://dx.doi.org/10.3390/ijerph19031257
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