Stem Cell Transplantation and Cell-Free Treatment for Periodontal Regeneration

Increasing attention has been paid to cell-based medicines. Many in vivo and in vitro studies have demonstrated the efficacy of stem cell transplantation for the regeneration of periodontal tissues over the past 20 years. Although positive evidence has accumulated regarding periodontal regeneration...

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Detalles Bibliográficos
Autores principales: Iwasaki, Kengo, Peng, Yihao, Kanda, Ryuhei, Umeda, Makoto, Ishikawa, Isao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8835344/
https://www.ncbi.nlm.nih.gov/pubmed/35162935
http://dx.doi.org/10.3390/ijms23031011
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author Iwasaki, Kengo
Peng, Yihao
Kanda, Ryuhei
Umeda, Makoto
Ishikawa, Isao
author_facet Iwasaki, Kengo
Peng, Yihao
Kanda, Ryuhei
Umeda, Makoto
Ishikawa, Isao
author_sort Iwasaki, Kengo
collection PubMed
description Increasing attention has been paid to cell-based medicines. Many in vivo and in vitro studies have demonstrated the efficacy of stem cell transplantation for the regeneration of periodontal tissues over the past 20 years. Although positive evidence has accumulated regarding periodontal regeneration using stem cells, the exact mechanism of tissue regeneration is still largely unknown. This review outlines the practicality and emerging problems of stem cell transplantation therapy for periodontal regeneration. In addition, possible solutions to these problems and cell-free treatment are discussed.
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spelling pubmed-88353442022-02-12 Stem Cell Transplantation and Cell-Free Treatment for Periodontal Regeneration Iwasaki, Kengo Peng, Yihao Kanda, Ryuhei Umeda, Makoto Ishikawa, Isao Int J Mol Sci Review Increasing attention has been paid to cell-based medicines. Many in vivo and in vitro studies have demonstrated the efficacy of stem cell transplantation for the regeneration of periodontal tissues over the past 20 years. Although positive evidence has accumulated regarding periodontal regeneration using stem cells, the exact mechanism of tissue regeneration is still largely unknown. This review outlines the practicality and emerging problems of stem cell transplantation therapy for periodontal regeneration. In addition, possible solutions to these problems and cell-free treatment are discussed. MDPI 2022-01-18 /pmc/articles/PMC8835344/ /pubmed/35162935 http://dx.doi.org/10.3390/ijms23031011 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Iwasaki, Kengo
Peng, Yihao
Kanda, Ryuhei
Umeda, Makoto
Ishikawa, Isao
Stem Cell Transplantation and Cell-Free Treatment for Periodontal Regeneration
title Stem Cell Transplantation and Cell-Free Treatment for Periodontal Regeneration
title_full Stem Cell Transplantation and Cell-Free Treatment for Periodontal Regeneration
title_fullStr Stem Cell Transplantation and Cell-Free Treatment for Periodontal Regeneration
title_full_unstemmed Stem Cell Transplantation and Cell-Free Treatment for Periodontal Regeneration
title_short Stem Cell Transplantation and Cell-Free Treatment for Periodontal Regeneration
title_sort stem cell transplantation and cell-free treatment for periodontal regeneration
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8835344/
https://www.ncbi.nlm.nih.gov/pubmed/35162935
http://dx.doi.org/10.3390/ijms23031011
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AT pengyihao stemcelltransplantationandcellfreetreatmentforperiodontalregeneration
AT kandaryuhei stemcelltransplantationandcellfreetreatmentforperiodontalregeneration
AT umedamakoto stemcelltransplantationandcellfreetreatmentforperiodontalregeneration
AT ishikawaisao stemcelltransplantationandcellfreetreatmentforperiodontalregeneration

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