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Latrotoxin-Induced Neuromuscular Junction Degeneration Reveals Urocortin 2 as a Critical Contributor to Motor Axon Terminal Regeneration

We used α-Latrotoxin (α-LTx), the main neurotoxic component of the black widow spider venom, which causes degeneration of the neuromuscular junction (NMJ) followed by a rapid and complete regeneration, as a molecular tool to identify by RNA transcriptomics factors contributing to the structural and...

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Detalles Bibliográficos
Autores principales: D’Este, Giorgia, Stazi, Marco, Negro, Samuele, Megighian, Aram, Lista, Florigio, Rossetto, Ornella, Montecucco, Cesare, Rigoni, Michela, Pirazzini, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8835473/
https://www.ncbi.nlm.nih.gov/pubmed/35163106
http://dx.doi.org/10.3390/ijms23031186