Cargando…
Salviolone from Salvia miltiorrhiza Roots Impairs Cell Cycle Progression, Colony Formation, and Metalloproteinase-2 Activity in A375 Melanoma Cells: Involvement of P21(Cip1/Waf1) Expression and STAT3 Phosphorylation
Melanoma is a highly malignant solid tumor characterized by an elevated growth and propagation rate. Since, often, melanoma treatment cannot prevent recurrences and the appearance of metastasis, new anti-melanoma agents need to be discovered. Salvia miltiorrhiza roots are a source of diterpenoid der...
Autores principales: | Zanrè, Valentina, Campagnari, Rachele, Cerulli, Antonietta, Masullo, Milena, Cardile, Alessia, Piacente, Sonia, Menegazzi, Marta |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8835475/ https://www.ncbi.nlm.nih.gov/pubmed/35163058 http://dx.doi.org/10.3390/ijms23031121 |
Ejemplares similares
-
Upregulation of miR-34a-5p, miR-20a-3p and miR-29a-3p by Onconase in A375 Melanoma Cells Correlates with the Downregulation of Specific Onco-Proteins
por: De Tomi, Elisa, et al.
Publicado: (2022) -
Onconase Restores Cytotoxicity in Dabrafenib-Resistant A375 Human Melanoma Cells and Affects Cell Migration, Invasion and Colony Formation Capability
por: Raineri, Alice, et al.
Publicado: (2019) -
Hyperforin Elicits Cytostatic/Cytotoxic Activity in Human Melanoma Cell Lines, Inhibiting Pro-Survival NF-κB, STAT3, AP1 Transcription Factors and the Expression of Functional Proteins Involved in Mitochondrial and Cytosolic Metabolism
por: Cardile, Alessia, et al.
Publicado: (2023) -
Metabolite Profiling of Helichrysum italicum Derived Food Supplements by (1)H-NMR-Based Metabolomics
por: Cerulli, Antonietta, et al.
Publicado: (2021) -
Natural Products Targeting ER Stress, and the Functional Link to Mitochondria
por: Martucciello, Stefania, et al.
Publicado: (2020)