Induced differentiation of acute myeloid leukemia cells by activation of Retinoid X and Liver X Receptors

Use of all-trans-retinoic acid (ATRA) as a differentiation agent has been limited to acute promyelocytic leukemia (APL) as non-APL leukemias are insensitive to ATRA. We recently demonstrated that the rexinoid, bexarotene, induces differentiation and therapeutic responses in patients with refractory...

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Detalles Bibliográficos
Autores principales: Sanchez, Patricia V., Glantz, Spencer T., Scotland, Sarah, Kasner, Margaret T., Carroll, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8835482/
https://www.ncbi.nlm.nih.gov/pubmed/23823656
http://dx.doi.org/10.1038/leu.2013.202

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8835482/
https://www.ncbi.nlm.nih.gov/pubmed/23823656
http://dx.doi.org/10.1038/leu.2013.202

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