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High Glucose Impairs Expression and Activation of MerTK in ARPE-19 Cells

MerTK (Mer Tyrosine Kinase) is a cell surface receptor that regulates phagocytosis of photoreceptor outer segments (POS) in retinal pigment epithelial (RPE) cells. POS phagocytosis is impaired in several pathologies, including diabetes. In this study, we investigate whether hyperglycemic conditions...

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Detalles Bibliográficos
Autores principales: Puddu, Alessandra, Ravera, Silvia, Panfoli, Isabella, Bertola, Nadia, Maggi, Davide
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8835591/
https://www.ncbi.nlm.nih.gov/pubmed/35163068
http://dx.doi.org/10.3390/ijms23031144