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Cell–Cell Mating Interactions: Overview and Potential of Single-Cell Force Spectroscopy

It is an understatement that mating and DNA transfer are key events for living organisms. Among the traits needed to facilitate mating, cell adhesion between gametes is a universal requirement. Thus, there should be specific properties for the adhesion proteins involved in mating. Biochemical and bi...

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Detalles Bibliográficos
Autores principales: Lipke, Peter N., Rauceo, Jason M., Viljoen, Albertus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8835621/
https://www.ncbi.nlm.nih.gov/pubmed/35163034
http://dx.doi.org/10.3390/ijms23031110
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author Lipke, Peter N.
Rauceo, Jason M.
Viljoen, Albertus
author_facet Lipke, Peter N.
Rauceo, Jason M.
Viljoen, Albertus
author_sort Lipke, Peter N.
collection PubMed
description It is an understatement that mating and DNA transfer are key events for living organisms. Among the traits needed to facilitate mating, cell adhesion between gametes is a universal requirement. Thus, there should be specific properties for the adhesion proteins involved in mating. Biochemical and biophysical studies have revealed structural information about mating adhesins, as well as their specificities and affinities, leading to some ideas about these specialized adhesion proteins. Recently, single-cell force spectroscopy (SCFS) has added important findings. In SCFS, mating cells are brought into contact in an atomic force microscope (AFM), and the adhesive forces are monitored through the course of mating. The results have shown some remarkable characteristics of mating adhesins and add knowledge about the design and evolution of mating adhesins.
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spelling pubmed-88356212022-02-12 Cell–Cell Mating Interactions: Overview and Potential of Single-Cell Force Spectroscopy Lipke, Peter N. Rauceo, Jason M. Viljoen, Albertus Int J Mol Sci Review It is an understatement that mating and DNA transfer are key events for living organisms. Among the traits needed to facilitate mating, cell adhesion between gametes is a universal requirement. Thus, there should be specific properties for the adhesion proteins involved in mating. Biochemical and biophysical studies have revealed structural information about mating adhesins, as well as their specificities and affinities, leading to some ideas about these specialized adhesion proteins. Recently, single-cell force spectroscopy (SCFS) has added important findings. In SCFS, mating cells are brought into contact in an atomic force microscope (AFM), and the adhesive forces are monitored through the course of mating. The results have shown some remarkable characteristics of mating adhesins and add knowledge about the design and evolution of mating adhesins. MDPI 2022-01-20 /pmc/articles/PMC8835621/ /pubmed/35163034 http://dx.doi.org/10.3390/ijms23031110 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Lipke, Peter N.
Rauceo, Jason M.
Viljoen, Albertus
Cell–Cell Mating Interactions: Overview and Potential of Single-Cell Force Spectroscopy
title Cell–Cell Mating Interactions: Overview and Potential of Single-Cell Force Spectroscopy
title_full Cell–Cell Mating Interactions: Overview and Potential of Single-Cell Force Spectroscopy
title_fullStr Cell–Cell Mating Interactions: Overview and Potential of Single-Cell Force Spectroscopy
title_full_unstemmed Cell–Cell Mating Interactions: Overview and Potential of Single-Cell Force Spectroscopy
title_short Cell–Cell Mating Interactions: Overview and Potential of Single-Cell Force Spectroscopy
title_sort cell–cell mating interactions: overview and potential of single-cell force spectroscopy
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8835621/
https://www.ncbi.nlm.nih.gov/pubmed/35163034
http://dx.doi.org/10.3390/ijms23031110
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