Retreatment of Chronic Hepatitis C Infection: Real-World Regimens and Outcomes From National Treatment Programs in Three Low- and Middle-Income Countries

Access to recommended second-line treatments is limited for patients who fail initial hepatitis C virus (HCV) therapy in low- and middle-income countries. Alternative regimens and associated outcomes are not well understood. Through a pooled analysis of national program data in Egypt, Georgia, and M...

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Autores principales: Boeke, Caroline E, Hiebert, Lindsey, Waked, Imam, Tsertsvadze, Tengiz, Sharvadze, Lali, Butsashvili, Maia, Zakalashvili, Mamuka, Naing, Win, Gupta, Neil, Kateera, Fredrick, McClure, Craig, Ward, John W, Ramers, Christian B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Brief Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8835629/
https://www.ncbi.nlm.nih.gov/pubmed/34014252
http://dx.doi.org/10.1093/cid/ciab461
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author Boeke, Caroline E
Hiebert, Lindsey
Waked, Imam
Tsertsvadze, Tengiz
Sharvadze, Lali
Butsashvili, Maia
Zakalashvili, Mamuka
Naing, Win
Gupta, Neil
Kateera, Fredrick
McClure, Craig
Ward, John W
Ramers, Christian B
author_facet Boeke, Caroline E
Hiebert, Lindsey
Waked, Imam
Tsertsvadze, Tengiz
Sharvadze, Lali
Butsashvili, Maia
Zakalashvili, Mamuka
Naing, Win
Gupta, Neil
Kateera, Fredrick
McClure, Craig
Ward, John W
Ramers, Christian B
author_sort Boeke, Caroline E
collection PubMed
description Access to recommended second-line treatments is limited for patients who fail initial hepatitis C virus (HCV) therapy in low- and middle-income countries. Alternative regimens and associated outcomes are not well understood. Through a pooled analysis of national program data in Egypt, Georgia, and Myanmar, we observed SVR rates >90% for alternative retreatment regimens.
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spelling pubmed-88356292022-02-14 Retreatment of Chronic Hepatitis C Infection: Real-World Regimens and Outcomes From National Treatment Programs in Three Low- and Middle-Income Countries Boeke, Caroline E Hiebert, Lindsey Waked, Imam Tsertsvadze, Tengiz Sharvadze, Lali Butsashvili, Maia Zakalashvili, Mamuka Naing, Win Gupta, Neil Kateera, Fredrick McClure, Craig Ward, John W Ramers, Christian B Clin Infect Dis Brief Reports Access to recommended second-line treatments is limited for patients who fail initial hepatitis C virus (HCV) therapy in low- and middle-income countries. Alternative regimens and associated outcomes are not well understood. Through a pooled analysis of national program data in Egypt, Georgia, and Myanmar, we observed SVR rates >90% for alternative retreatment regimens. Oxford University Press 2021-07-03 /pmc/articles/PMC8835629/ /pubmed/34014252 http://dx.doi.org/10.1093/cid/ciab461 Text en © The Author(s) 2021. Published by Oxford University Press for the Infectious Diseases Society of America. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (https://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Brief Reports
Boeke, Caroline E
Hiebert, Lindsey
Waked, Imam
Tsertsvadze, Tengiz
Sharvadze, Lali
Butsashvili, Maia
Zakalashvili, Mamuka
Naing, Win
Gupta, Neil
Kateera, Fredrick
McClure, Craig
Ward, John W
Ramers, Christian B
Retreatment of Chronic Hepatitis C Infection: Real-World Regimens and Outcomes From National Treatment Programs in Three Low- and Middle-Income Countries
title Retreatment of Chronic Hepatitis C Infection: Real-World Regimens and Outcomes From National Treatment Programs in Three Low- and Middle-Income Countries
title_full Retreatment of Chronic Hepatitis C Infection: Real-World Regimens and Outcomes From National Treatment Programs in Three Low- and Middle-Income Countries
title_fullStr Retreatment of Chronic Hepatitis C Infection: Real-World Regimens and Outcomes From National Treatment Programs in Three Low- and Middle-Income Countries
title_full_unstemmed Retreatment of Chronic Hepatitis C Infection: Real-World Regimens and Outcomes From National Treatment Programs in Three Low- and Middle-Income Countries
title_short Retreatment of Chronic Hepatitis C Infection: Real-World Regimens and Outcomes From National Treatment Programs in Three Low- and Middle-Income Countries
title_sort retreatment of chronic hepatitis c infection: real-world regimens and outcomes from national treatment programs in three low- and middle-income countries
topic Brief Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8835629/
https://www.ncbi.nlm.nih.gov/pubmed/34014252
http://dx.doi.org/10.1093/cid/ciab461
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