Cargando…

Soluble Endoglin Stimulates Inflammatory and Angiogenic Responses in Microglia That Are Associated with Endothelial Dysfunction

Increased soluble endoglin (sENG) has been observed in human brain arteriovenous malformations (bAVMs). In addition, the overexpression of sENG in concurrence with vascular endothelial growth factor (VEGF)-A has been shown to induce dysplastic vessel formation in mouse brains. However, the underlyin...

Descripción completa

Detalles Bibliográficos
Autores principales:	Park, Eun S., Kim, Sehee, Yao, Derek C., Savarraj, Jude P. J., Choi, Huimahn Alex, Chen, Peng Roc, Kim, Eunhee
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8835690/ https://www.ncbi.nlm.nih.gov/pubmed/35163148 http://dx.doi.org/10.3390/ijms23031225

Ejemplares similares

High Soluble Endoglin Levels Do Not Induce Endothelial Dysfunction in Mouse Aorta
por: Nemeckova, Ivana, et al.
Publicado: (2015)

MMP-15 Is Upregulated in Preeclampsia, but Does Not Cleave Endoglin to Produce Soluble Endoglin
por: Kaitu’u-Lino, Tu’uhevaha J., et al.
Publicado: (2012)

Circulating soluble endoglin modifies the inflammatory response in mice
por: Ruiz-Remolina, Laura, et al.
Publicado: (2017)

Role of soluble endoglin in BMP9 signaling
por: Lawera, Aleksandra, et al.
Publicado: (2019)

Curcuminoids Inhibit Angiogenic Behaviors of Human Umbilical Vein Endothelial Cells via Endoglin/Smad1 Signaling
por: Chou, Yi-Fan, et al.
Publicado: (2022)

High concentrations of soluble endoglin can inhibit BMP9 signaling in non-endothelial cells
por: Andersson-Rusch, Clara, et al.
Publicado: (2023)

Accuracy of Soluble Endoglin for Diagnosis of Preeclampsia and its Severity
por: Nikuei, Pooneh, et al.
Publicado: (2017)

The relationship of the neo-angiogenic marker, endoglin, with response to neoadjuvant chemotherapy in breast cancer
por: Beresford, M J, et al.
Publicado: (2006)

Role of Endoglin (CD105) in the Progression of Hepatocellular Carcinoma and Anti-Angiogenic Therapy
por: Kasprzak, Aldona, et al.
Publicado: (2018)

Endoglin (CD105) and VEGF as potential angiogenic and dissemination markers for colorectal cancer
por: Nogués, Ana, et al.
Publicado: (2020)

Bioenergetic effects of hydrogen sulfide suppress soluble Flt-1 and soluble endoglin in cystathionine gamma-lyase compromised endothelial cells
por: Sanchez-Aranguren, Lissette Carolina, et al.
Publicado: (2020)

High-Protein Supplementation and Neuromuscular Electric Stimulation after Aneurysmal Subarachnoid Hemorrhage Increases Systemic Amino Acid and Oxidative Metabolism: A Plasma Metabolomics Approach
por: Gusdon, Aaron M, et al.
Publicado: (2023)

The Potential Role of MiRs-139-5p and -454-3p in Endoglin-Knockdown-Induced Angiogenic Dysfunction in HUVECs
por: Cannavicci, Anthony, et al.
Publicado: (2023)

Endoglin (CD105) and proliferation index in recurrent glioblastoma treated with anti-angiogenic therapy
por: Bastos, António G. P., et al.
Publicado: (2022)

Brain injury, endothelial injury and inflammatory markers are elevated and express sex-specific alterations after COVID-19
por: Savarraj, Jude, et al.
Publicado: (2021)

Diagnostic and prognostic significance of serum soluble endoglin levels in preeclampsia and eclampsia
por: Sachan, Rekha, et al.
Publicado: (2016)

Long term effects of soluble endoglin and mild hypercholesterolemia in mice hearts
por: Vitverova, Barbora, et al.
Publicado: (2020)

Time Course of Peripheral Leukocytosis and Clinical Outcomes After Aneurysmal Subarachnoid Hemorrhage
por: Gusdon, Aaron M., et al.
Publicado: (2021)

Endoglin Requirement for BMP9 Signaling in Endothelial Cells Reveals New Mechanism of Action for Selective Anti-Endoglin Antibodies
por: Nolan-Stevaux, Olivier, et al.
Publicado: (2012)

Systemic inflammatory markers of persistent cerebral edema after aneurysmal subarachnoid hemorrhage
por: Ahn, Sung-Ho, et al.
Publicado: (2022)

Endoglin – a marker of vascular endothelial cell proliferation in cancer
por: Kopczyńska, Ewa, et al.
Publicado: (2012)

Plasma Concentrations of Soluble Endoglin versus Standard Evaluation in Patients with Suspected Preeclampsia
por: Rana, Sarosh, et al.
Publicado: (2012)

Generation of a Soluble Form of Human Endoglin Fused to Green Fluorescent Protein
por: Ruiz-Llorente, Lidia, et al.
Publicado: (2021)

Prognostic value of soluble endoglin in patients with septic shock and severe COVID-19
por: Tomášková, Veronika, et al.
Publicado: (2022)

Resveratrol inhibits release of soluble fms-like tyrosine kinase (sFlt-1) and soluble endoglin and improves vascular dysfunction – implications as a preeclampsia treatment
por: Hannan, Natalie J., et al.
Publicado: (2017)

Monoclonal anti-endoglin antibody TRC105 (carotuximab) prevents hypercholesterolemia and hyperglycemia-induced endothelial dysfunction in human aortic endothelial cells
por: Tripska, Katarina, et al.
Publicado: (2022)

Immuno-Expression of Endoglin and Smooth Muscle Actin in the Vessels of Brain Metastases. Is There a Rational for Anti-Angiogenic Therapy?
por: Barresi, Valeria, et al.
Publicado: (2014)

Deficiency for endoglin in tumor vasculature weakens the endothelial barrier to metastatic dissemination
por: Anderberg, Charlotte, et al.
Publicado: (2013)

Increased plasma soluble endoglin levels as an indicator of cardiovascular alterations in hypertensive and diabetic patients
por: Blázquez-Medela, Ana M, et al.
Publicado: (2010)

High Soluble Endoglin Levels Affect Aortic Vascular Function during Mice Aging
por: Nejmanová, Iveta, et al.
Publicado: (2021)

Labetalol and soluble endoglin aggravate bile acid retention in mice with ethinylestradiol-induced cholestasis
por: Cristina Igreja Sá, Ivone, et al.
Publicado: (2023)

Low Plasma Levels of Soluble Endoglin and Cardiovascular Events in Patients Undergoing Coronary Angiography
por: Saita, Emi, et al.
Publicado: (2023)

Peripheral eosinophil trends and clinical outcomes after non-traumatic subarachnoid hemorrhage
por: Gonzalez Gomez, Hugo, et al.
Publicado: (2023)

MMP-12, Secreted by Pro-Inflammatory Macrophages, Targets Endoglin in Human Macrophages and Endothelial Cells
por: Aristorena, Mikel, et al.
Publicado: (2019)

Microglial Phenotyping in Neurodegenerative Disease Brains: Identification of Reactive Microglia with an Antibody to Variant of CD105/Endoglin
por: Walker, Douglas G., et al.
Publicado: (2019)

CFTR dysfunction increases endoglin and TGF‐β signaling in airway epithelia
por: Nicola, Teodora, et al.
Publicado: (2019)

Endoglin: Beyond the Endothelium
por: Schoonderwoerd, Mark J. A., et al.
Publicado: (2020)

ENDOGLIN Is Dispensable for Vasculogenesis, but Required for Vascular Endothelial Growth Factor-Induced Angiogenesis
por: Liu, Zhen, et al.
Publicado: (2014)

Dysregulated Hypothalamic–Pituitary–Adrenal Axis Is Associated With Increased Inflammation and Worse Outcomes After Ischemic Stroke in Diabetic Mice
por: Kim, Sehee, et al.
Publicado: (2022)

Elevated Levels of Soluble Axl (sAxl) Regulates Key Angiogenic Molecules to Induce Placental Endothelial Dysfunction and a Preeclampsia-Like Phenotype
por: Gui, Shunping, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_60bcq8aosndcaa0hrb3o1lnnd8