Cargando…

MiR-29a Curbs Hepatocellular Carcinoma Incidence via Targeting of HIF-1α and ANGPT2

A high-fat diet is responsible for hepatic fat accumulation that sustains chronic liver damage and increases the risks of steatosis and hepatocellular carcinoma (HCC). MicroRNA-29a (miR-29a), a key regulator of cellular behaviors, is present in anti-fibrosis and modulator tumorigenesis. However, the...

Descripción completa

Detalles Bibliográficos
Autores principales:	Huang, Ying-Hsien, Lian, Wei-Shiung, Wang, Feng-Sheng, Wang, Pei-Wen, Lin, Hung-Yu, Tsai, Ming-Chao, Yang, Ya-Ling
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8835722/ https://www.ncbi.nlm.nih.gov/pubmed/35163556 http://dx.doi.org/10.3390/ijms23031636

Ejemplares similares

New Insights into the Role of miR-29a in Hepatocellular Carcinoma: Implications in Mechanisms and Theragnostics
por: Yang, Ya-Ling, et al.
Publicado: (2021)

MIR29A Impedes Metastatic Behaviors in Hepatocellular Carcinoma via Targeting LOX, LOXL2, and VEGFA
por: Yang, Ya-Ling, et al.
Publicado: (2021)

miR-29cb2 promotes angiogenesis and osteogenesis by inhibiting HIF-3α in bone
por: Ouyang, Liping, et al.
Publicado: (2021)

BNIP3 promotes HIF‐1α‐driven melanoma growth by curbing intracellular iron homeostasis
por: Vara‐Pérez, Mónica, et al.
Publicado: (2021)

MiR-452 Regulates C2C12 Myoblast Proliferation and Differentiation via Targeting ANGPT1
por: Yang, Lingzhi, et al.
Publicado: (2021)

miR-205-5p inhibits human endometriosis progression by targeting ANGPT2 in endometrial stromal cells
por: Zhou, Chen-Fei, et al.
Publicado: (2019)

Dual targeting of ANGPT1 and TGFBR2 genes by miR-204 controls angiogenesis in breast cancer
por: Flores-Pérez, Ali, et al.
Publicado: (2016)

miR-135a-5p inhibits tumor invasion by targeting ANGPT2 in gallbladder cancer
por: Diao, Haiyan, et al.
Publicado: (2021)

Clonal Dominance With Retroviral Vector Insertions Near the ANGPT1 and ANGPT2 Genes in a Human Xenotransplant Mouse Model
por: Haemmerle, Reinhard, et al.
Publicado: (2014)

Correction to: miR-205-5p inhibits human endometriosis progression by targeting ANGPT2 in endometrial stromal cells
por: Zhou, Chen-Fei, et al.
Publicado: (2020)

The Role of miR-29a in the Regulation, Function, and Signaling of Liver Fibrosis
por: Huang, Ying-Hsien, et al.
Publicado: (2018)

USP29-mediated HIF1α stabilization is associated with Sorafenib resistance of hepatocellular carcinoma cells by upregulating glycolysis
por: Gao, Ruize, et al.
Publicado: (2021)

LINC00184 involved in the regulatory network of ANGPT2 via ceRNA mediated miR-145 inhibition in gastric cancer
por: Piao, Hai-yan, et al.
Publicado: (2021)

miR-29a Modulates GSK3β/SIRT1-Linked Mitochondrial Proteostatic Stress to Ameliorate Mouse Non-Alcoholic Steatohepatitis
por: Yang, Ya-Ling, et al.
Publicado: (2020)

Down‐regulation of TIMP2 by HIF‐1α/miR‐210/HIF‐3α regulatory feedback circuit enhances cancer metastasis in hepatocellular carcinoma
por: Kai, Alan Ka‐Lun, et al.
Publicado: (2016)

ANGPT2 and NOS3 Polymorphisms and Clinical Outcome in Advanced Hepatocellular Carcinoma Patients Receiving Sorafenib
por: Marisi, Giorgia, et al.
Publicado: (2019)

MiR-3662 suppresses hepatocellular carcinoma growth through inhibition of HIF-1α-mediated Warburg effect
por: Chen, Zhiqiang, et al.
Publicado: (2018)

Exosomal miR-3682-3p Suppresses Angiogenesis by Targeting ANGPT1 via the RAS-MEK1/2-ERK1/2 Pathway in Hepatocellular Carcinoma
por: Dong, Shuang-Shuang, et al.
Publicado: (2021)

Loss of miR-145-5p Causes Ceruloplasmin Interference with PHD-Iron Axis and HIF-2α Stabilization in Lung Adenocarcinoma-Mediated Angiogenesis
por: Tsai, Ying-Ming, et al.
Publicado: (2020)

Mutual Regulation of MiR-199a-5p and HIF-1α Modulates the Warburg Effect in Hepatocellular Carcinoma
por: Li, Binkui, et al.
Publicado: (2017)

Tissue-specific epigenetics of atherosclerosis-related ANGPT and ANGPTL genes
por: Ehrlich, Kenneth C, et al.
Publicado: (2019)

Angpt2/Tie2 autostimulatory loop controls tumorigenesis
por: Karabid, Ninelia Minaskan, et al.
Publicado: (2022)

Genetic association of ANGPT2 with primary open-angle glaucoma
por: He, Jing Na, et al.
Publicado: (2022)

MiR-210 regulates lung adenocarcinoma by targeting HIF-1α
por: Cao, Guolei, et al.
Publicado: (2023)

Angpt2 Induces Mesangial Cell Apoptosis through the MicroRNA-33-5p-SOCS5 Loop in Diabetic Nephropathy
por: Tsai, Yi-Chun, et al.
Publicado: (2018)

CircPVT1 Promoted the Progression of Breast Cancer by Regulating MiR-29a-3p-Mediated AGR2-HIF-1α Pathway
por: Wang, Jing, et al.
Publicado: (2020)

Effect of miR‑29a‑3p in exosomes on glioma cells by regulating the PI3K/AKT/HIF‑1α pathway
por: Liu, Zeqiang, et al.
Publicado: (2023)

Germline Genetic Variants in TEK, ANGPT1, ANGPT2, MMP9, FGF2 and VEGFA Are Associated with Pathologic Complete Response to Bevacizumab in Breast Cancer Patients
por: Makhoul, Issam, et al.
Publicado: (2017)

Immune-related gene ANGPT1 is an adverse biomarker for endometrial carcinoma
por: Nong, Binbin, et al.
Publicado: (2021)

CENPB promotes the proliferation of hepatocellular carcinoma and is directly regulated by miR-29a
por: Wang, Xuyang, et al.
Publicado: (2023)

Effects of metal nanoparticles on tight junction-associated proteins via HIF-1α/miR-29b/MMPs pathway in human epidermal keratinocytes
por: Yuan, Jiali, et al.
Publicado: (2021)

miR-592/WSB1/HIF-1α axis inhibits glycolytic metabolism to decrease hepatocellular carcinoma growth
por: Jia, Yan-Yan, et al.
Publicado: (2016)

miR-138-5p Inhibits Vascular Mimicry by Targeting the HIF-1α/VEGFA Pathway in Hepatocellular Carcinoma
por: Liu, Hongwei, et al.
Publicado: (2022)

Expression and significance of MMP2 and HIF-1α in hepatocellular carcinoma
por: WANG, BIN, et al.
Publicado: (2014)

Curbing Inflammation
por: Landis, R. Clive, et al.
Publicado: (2013)

MYBL1 induces transcriptional activation of ANGPT2 to promote tumor angiogenesis and confer sorafenib resistance in human hepatocellular carcinoma
por: Zhu, Jinrong, et al.
Publicado: (2022)

Ischemic Postconditioning Protects Against Intestinal Ischemia/Reperfusion Injury via the HIF-1α/miR-21 Axis
por: Jia, Zhongzhi, et al.
Publicado: (2017)

Knockdown of CDR1as Decreases Differentiation of Goat Skeletal Muscle Satellite Cells via Upregulating miR-27a-3p to Inhibit ANGPT1
por: Kyei, Bismark, et al.
Publicado: (2022)

0737. Statins protect the vasculature from excessive angpt-2 production in sepsis
por: Thamm, K, et al.
Publicado: (2014)

Distinct Roles of VEGFA and ANGPT2 in Lung Adenocarcinoma and Squamous Cell Carcinoma
por: Qin, Shuang, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_ki5erfginp1l2003d63qj4plkv