A Multi-Disulfide Receptor-Binding Domain (RBD) of the SARS-CoV-2 Spike Protein Expressed in E. coli Using a SEP-Tag Produces Antisera Interacting with the Mammalian Cell Expressed Spike (S1) Protein

An Escherichia coli (E. coli) production of the receptor-binding domain (RBD) of the SARS-CoV-2 (isolate Wuhan-Hu-1) spike protein would significantly accelerate the search for anti-COVID-19 therapeutics because of its versatility and low cost. However, RBD contains four disulfide bonds and its expr...

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Detalles Bibliográficos
Autores principales: Brindha, Subbaian, Kuroda, Yutaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8835783/
https://www.ncbi.nlm.nih.gov/pubmed/35163624
http://dx.doi.org/10.3390/ijms23031703

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8835783/
https://www.ncbi.nlm.nih.gov/pubmed/35163624
http://dx.doi.org/10.3390/ijms23031703

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