Multidimensional Phylogenetic Metrics Identify Class I Aminoacyl-tRNA Synthetase Evolutionary Mosaicity and Inter-Modular Coupling

The role of aminoacyl-tRNA synthetases (aaRS) in the emergence and evolution of genetic coding poses challenging questions concerning their provenance. We seek evidence about their ancestry from curated structure-based multiple sequence alignments of a structurally invariant “scaffold” shared by all...

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Detalles Bibliográficos
Autores principales: Carter, Charles W., Popinga, Alex, Bouckaert, Remco, Wills, Peter R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8835825/
https://www.ncbi.nlm.nih.gov/pubmed/35163448
http://dx.doi.org/10.3390/ijms23031520

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