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Cassiaside C Inhibits M1 Polarization of Macrophages by Downregulating Glycolysis

Classically activated M1 macrophages reprogram their metabolism towards enhanced glycolysis to obtain energy and produce pro-inflammatory cytokines after activation by mammalian target of rapamycin complex 1 (mTORC1) and hypoxia-inducible factor (HIF)-1α. Thus, a strategy that constrains M1 polariza...

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Detalles Bibliográficos
Autores principales:	Kim, Ye Jin, Lee, Sungwoo, Jin, Jonghwa, Woo, Hyein, Choi, Yeon-Kyung, Park, Keun-Gyu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8835843/ https://www.ncbi.nlm.nih.gov/pubmed/35163619 http://dx.doi.org/10.3390/ijms23031696

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