Cargando…
Nanoparticles in Clinical Translation for Cancer Therapy
The advent of cancer therapeutics brought a paradigm shift from conventional therapy to precision medicine. The new therapeutic modalities accomplished through the properties of nanomaterials have extended their scope in cancer therapy beyond conventional drug delivery. Nanoparticles can be channele...
Autores principales: | , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8835852/ https://www.ncbi.nlm.nih.gov/pubmed/35163607 http://dx.doi.org/10.3390/ijms23031685 |
_version_ | 1784649534266146816 |
---|---|
author | Mundekkad, Deepa Cho, William C. |
author_facet | Mundekkad, Deepa Cho, William C. |
author_sort | Mundekkad, Deepa |
collection | PubMed |
description | The advent of cancer therapeutics brought a paradigm shift from conventional therapy to precision medicine. The new therapeutic modalities accomplished through the properties of nanomaterials have extended their scope in cancer therapy beyond conventional drug delivery. Nanoparticles can be channeled in cancer therapy to encapsulate active pharmaceutical ingredients and deliver them to the tumor site in a more efficient manner. This review enumerates various types of nanoparticles that have entered clinical trials for cancer treatment. The obstacles in the journey of nanodrug from clinic to market are reviewed. Furthermore, the latest developments in using nanoparticles in cancer therapy are also highlighted. |
format | Online Article Text |
id | pubmed-8835852 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-88358522022-02-12 Nanoparticles in Clinical Translation for Cancer Therapy Mundekkad, Deepa Cho, William C. Int J Mol Sci Review The advent of cancer therapeutics brought a paradigm shift from conventional therapy to precision medicine. The new therapeutic modalities accomplished through the properties of nanomaterials have extended their scope in cancer therapy beyond conventional drug delivery. Nanoparticles can be channeled in cancer therapy to encapsulate active pharmaceutical ingredients and deliver them to the tumor site in a more efficient manner. This review enumerates various types of nanoparticles that have entered clinical trials for cancer treatment. The obstacles in the journey of nanodrug from clinic to market are reviewed. Furthermore, the latest developments in using nanoparticles in cancer therapy are also highlighted. MDPI 2022-02-01 /pmc/articles/PMC8835852/ /pubmed/35163607 http://dx.doi.org/10.3390/ijms23031685 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Mundekkad, Deepa Cho, William C. Nanoparticles in Clinical Translation for Cancer Therapy |
title | Nanoparticles in Clinical Translation for Cancer Therapy |
title_full | Nanoparticles in Clinical Translation for Cancer Therapy |
title_fullStr | Nanoparticles in Clinical Translation for Cancer Therapy |
title_full_unstemmed | Nanoparticles in Clinical Translation for Cancer Therapy |
title_short | Nanoparticles in Clinical Translation for Cancer Therapy |
title_sort | nanoparticles in clinical translation for cancer therapy |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8835852/ https://www.ncbi.nlm.nih.gov/pubmed/35163607 http://dx.doi.org/10.3390/ijms23031685 |
work_keys_str_mv | AT mundekkaddeepa nanoparticlesinclinicaltranslationforcancertherapy AT chowilliamc nanoparticlesinclinicaltranslationforcancertherapy |