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Nanoparticles in Clinical Translation for Cancer Therapy

The advent of cancer therapeutics brought a paradigm shift from conventional therapy to precision medicine. The new therapeutic modalities accomplished through the properties of nanomaterials have extended their scope in cancer therapy beyond conventional drug delivery. Nanoparticles can be channele...

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Detalles Bibliográficos
Autores principales: Mundekkad, Deepa, Cho, William C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8835852/
https://www.ncbi.nlm.nih.gov/pubmed/35163607
http://dx.doi.org/10.3390/ijms23031685
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author Mundekkad, Deepa
Cho, William C.
author_facet Mundekkad, Deepa
Cho, William C.
author_sort Mundekkad, Deepa
collection PubMed
description The advent of cancer therapeutics brought a paradigm shift from conventional therapy to precision medicine. The new therapeutic modalities accomplished through the properties of nanomaterials have extended their scope in cancer therapy beyond conventional drug delivery. Nanoparticles can be channeled in cancer therapy to encapsulate active pharmaceutical ingredients and deliver them to the tumor site in a more efficient manner. This review enumerates various types of nanoparticles that have entered clinical trials for cancer treatment. The obstacles in the journey of nanodrug from clinic to market are reviewed. Furthermore, the latest developments in using nanoparticles in cancer therapy are also highlighted.
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spelling pubmed-88358522022-02-12 Nanoparticles in Clinical Translation for Cancer Therapy Mundekkad, Deepa Cho, William C. Int J Mol Sci Review The advent of cancer therapeutics brought a paradigm shift from conventional therapy to precision medicine. The new therapeutic modalities accomplished through the properties of nanomaterials have extended their scope in cancer therapy beyond conventional drug delivery. Nanoparticles can be channeled in cancer therapy to encapsulate active pharmaceutical ingredients and deliver them to the tumor site in a more efficient manner. This review enumerates various types of nanoparticles that have entered clinical trials for cancer treatment. The obstacles in the journey of nanodrug from clinic to market are reviewed. Furthermore, the latest developments in using nanoparticles in cancer therapy are also highlighted. MDPI 2022-02-01 /pmc/articles/PMC8835852/ /pubmed/35163607 http://dx.doi.org/10.3390/ijms23031685 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Mundekkad, Deepa
Cho, William C.
Nanoparticles in Clinical Translation for Cancer Therapy
title Nanoparticles in Clinical Translation for Cancer Therapy
title_full Nanoparticles in Clinical Translation for Cancer Therapy
title_fullStr Nanoparticles in Clinical Translation for Cancer Therapy
title_full_unstemmed Nanoparticles in Clinical Translation for Cancer Therapy
title_short Nanoparticles in Clinical Translation for Cancer Therapy
title_sort nanoparticles in clinical translation for cancer therapy
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8835852/
https://www.ncbi.nlm.nih.gov/pubmed/35163607
http://dx.doi.org/10.3390/ijms23031685
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