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GFP–Margatoxin, a Genetically Encoded Fluorescent Ligand to Probe Affinity of Kv1.3 Channel Blockers

Peptide pore blockers and their fluorescent derivatives are useful molecular probes to study the structure and functions of the voltage-gated potassium Kv1.3 channel, which is considered as a pharmacological target in the treatment of autoimmune and neurological disorders. We present Kv1.3 fluoresce...

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Detalles Bibliográficos
Autores principales:	Denisova, Kristina R., Orlov, Nikita A., Yakimov, Sergey A., Kryukova, Elena A., Dolgikh, Dmitry A., Kirpichnikov, Mikhail P., Feofanov, Alexey V., Nekrasova, Oksana V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8835862/ https://www.ncbi.nlm.nih.gov/pubmed/35163644 http://dx.doi.org/10.3390/ijms23031724

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