Global Loss of Core 1-Derived O-Glycans in Mice Leads to High Mortality Due to Acute Kidney Failure and Gastric Ulcers

The core 1 structure is the major constituent of mucin-type O-glycans, which are added via glycosylation—a posttranslational modification present on membrane-bound and secretory proteins. Core 1 β1,3-galactosyltransferase (C1galt1), an enzyme that synthesizes the core 1 structure, requires Cosmc, a...

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Detalles Bibliográficos
Autores principales: Suzuki, Riku, Nakamura, Yuki, Koiwai, Rikako, Fuseya, Sayaka, Murakami, Yuka, Hagiwara, Kozue, Sato, Takashi, Takahashi, Satoru, Kudo, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8835874/
https://www.ncbi.nlm.nih.gov/pubmed/35163200
http://dx.doi.org/10.3390/ijms23031273

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8835874/
https://www.ncbi.nlm.nih.gov/pubmed/35163200
http://dx.doi.org/10.3390/ijms23031273

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