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Identification of NLRP3(PYD) Homo-Oligomerization Inhibitors with Anti-Inflammatory Activity
Inflammasomes are multiprotein complexes that represent critical elements of the inflammatory response. The dysregulation of the best-characterized complex, the NLRP3 inflammasome, has been linked to the pathogenesis of diseases such as multiple sclerosis, type 2 diabetes mellitus, Alzheimer’s disea...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8835912/ https://www.ncbi.nlm.nih.gov/pubmed/35163573 http://dx.doi.org/10.3390/ijms23031651 |