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Identification of NLRP3(PYD) Homo-Oligomerization Inhibitors with Anti-Inflammatory Activity

Inflammasomes are multiprotein complexes that represent critical elements of the inflammatory response. The dysregulation of the best-characterized complex, the NLRP3 inflammasome, has been linked to the pathogenesis of diseases such as multiple sclerosis, type 2 diabetes mellitus, Alzheimer’s disea...

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Detalles Bibliográficos
Autores principales: Moasses Ghafary, Soroush, Soriano-Teruel, Paula M., Lotfollahzadeh, Shima, Sancho, Mónica, Serrano-Candelas, Eva, Karami, Fatemeh, Barigye, Stephen J., Fernández-Pérez, Iván, Gozalbes, Rafael, Nikkhah, Maryam, Orzáez, Mar, Hosseinkhani, Saman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8835912/
https://www.ncbi.nlm.nih.gov/pubmed/35163573
http://dx.doi.org/10.3390/ijms23031651

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