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MHY2245, a Sirtuin Inhibitor, Induces Cell Cycle Arrest and Apoptosis in HCT116 Human Colorectal Cancer Cells

Sirtuins (SIRTs), which are nicotinamide adenine dinucleotide-dependent class III histone deacetylases, regulate cell division, survival, and senescence. Although sirtinol, a synthetic SIRT inhibitor, is known to exhibit antitumor effects, its mechanism of action is not well understood. Therefore, w...

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Detalles Bibliográficos
Autores principales:	Kang, Yong Jung, Jang, Jung Yoon, Kwon, Young Hoon, Lee, Jun Ho, Lee, Sanggwon, Park, Yujin, Jung, Young-Suk, Im, Eunok, Moon, Hyung Ryong, Chung, Hae Young, Kim, Nam Deuk
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8835956/ https://www.ncbi.nlm.nih.gov/pubmed/35163511 http://dx.doi.org/10.3390/ijms23031590

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